Major histocompatibility complex class I deficiency is a rare immunodeficiency disorder characterized by the absence or dysfunction of class I MHC molecules, leading to impaired cytotoxic T-cell responses. This condition is clinically significant as it predisposes individuals to severe viral infections and certain malignancies. Accurate coding with ICD-10 Code D81.6 is essential for proper diagnosis, documentation, medical billing, and public health reporting.
ICD-10 Code D81.6 represents Major histocompatibility complex class I deficiency, a genetic disorder that affects the immune system's ability to recognize and respond to infected or malignant cells. This code should be used in clinical documentation and billing when diagnosing patients with this specific immunodeficiency, ensuring accurate representation of the patient's health status and facilitating appropriate treatment and management.
Major histocompatibility complex class I deficiency is primarily caused by genetic mutations affecting the expression of MHC class I molecules on cell surfaces. This deficiency leads to a compromised immune response, particularly against viral infections, necessitating prompt medical attention to prevent severe complications.
In SOAP notes, ICD-10 Code D81.6 is utilized to document the diagnosis of Major histocompatibility complex class I deficiency, aiding in the assessment of symptoms, clinical findings, and treatment plans. This code is relevant in both acute and chronic care settings, ensuring comprehensive patient management.
ICD-10 Code D81.6 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Major histocompatibility complex class I deficiency. This code is crucial for ensuring continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Management of Major histocompatibility complex class I deficiency often requires hospitalization due to the risk of severe infections. Treatment focuses on supportive care and preventive measures.


HIPAA-compliant and designed with privacy in mind, your patient’s data is protected. Focus on care while we safeguard your information.
Learn moreICD-10 Code D81.6 is critical in medical billing, particularly in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 99214 | Established patient office visit, moderate complexity. |
| 36415 | Collection of venous blood by venipuncture. |
| 85025 | Complete blood count with automated differential. |
| 90715 | Immunization administration for vaccines. |
Common Questions About Using ICD-10 Code D81.6 for Major histocompatibility complex class I deficiency
What are the common symptoms of Major histocompatibility complex class I deficiency?
Common symptoms include recurrent viral infections, unusual infections requiring hospitalization, and a family history of immunodeficiency disorders. Patients may also experience fatigue and general malaise.
How is Major histocompatibility complex class I deficiency diagnosed?
Diagnosis is typically made through immunological testing that reveals absent or reduced MHC class I expression, along with a clinical history of recurrent infections.
What treatment options are available for this condition?
Treatment may include immunoglobulin replacement therapy, prophylactic antibiotics for recurrent infections, and education on infection prevention strategies.
Is Major histocompatibility complex class I deficiency hereditary?
Yes, this condition is often caused by genetic mutations and can be inherited in an autosomal recessive manner, affecting family members.
Clinical Notes
SOAP notes
DAP notes
AI medical notes