Adenosine deaminase (ADA) deficiency is a rare genetic disorder that leads to severe combined immunodeficiency (SCID). It is caused by mutations in the ADA gene, resulting in the accumulation of toxic metabolites that impair lymphocyte function. Accurate coding with ICD-10 Code D81.3 is essential for proper diagnosis, documentation, and billing, facilitating appropriate patient management and public health reporting.
ICD-10 Code D81.3 represents Adenosine deaminase (ADA) deficiency, a genetic disorder characterized by the absence or deficiency of the ADA enzyme. This condition leads to immunodeficiency, making patients susceptible to infections. The code should be used in clinical documentation and billing when diagnosing patients with confirmed ADA deficiency, ensuring accurate representation of the patient's health status.
Adenosine deaminase (ADA) deficiency is caused by mutations in the ADA gene, leading to the accumulation of toxic metabolites that adversely affect lymphocyte development and function. This condition progresses rapidly, resulting in severe immunodeficiency that necessitates immediate medical intervention.
ICD-10 Code D81.3 is utilized in SOAP notes to document the clinical presentation, assessment, and treatment of patients with ADA deficiency. It plays a crucial role in both acute and chronic care settings, ensuring comprehensive documentation of the patient's condition and guiding clinical decision-making.
In SOAP notes, ICD-10 Code D81.3 connects subjective patient reports and objective clinical findings to a formal diagnosis of ADA deficiency. This code is vital for ensuring continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Adenosine deaminase deficiency requires urgent medical attention, often necessitating hospitalization for management.


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Learn moreICD-10 Code D81.3 is critical in medical billing, particularly in hospital and infectious disease care settings.
| CPT Code | Description |
|---|---|
| 36415 | Collection of venous blood by venipuncture. |
| 90715 | Immunization administration for immunoglobulin therapy. |
| 38220 | Bone marrow aspiration and/or biopsy. |
Common Questions About Using ICD-10 Code D81.3 for Adenosine deaminase [ADA] deficiency
What are the common symptoms of Adenosine deaminase deficiency?
Common symptoms include recurrent infections, failure to thrive, and lymphopenia. Patients may experience severe respiratory infections and other opportunistic infections due to compromised immune function.
How is Adenosine deaminase deficiency treated?
Treatment typically involves immunoglobulin replacement therapy and may include hematopoietic stem cell transplantation for a definitive cure. Supportive care is crucial to manage infections.
Is Adenosine deaminase deficiency hereditary?
Yes, Adenosine deaminase deficiency is an autosomal recessive genetic disorder, meaning both parents must carry the mutated gene for a child to be affected.
What is the prognosis for patients with Adenosine deaminase deficiency?
Without treatment, the prognosis is poor due to severe immunodeficiency. However, with appropriate management, including stem cell transplantation, patients can lead healthier lives.
Clinical Notes
SOAP notes
DAP notes
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