Severe combined immunodeficiency with reticular dysgenesis is a rare genetic disorder characterized by the absence of T and B lymphocytes, leading to severe immune deficiency. This condition is caused by mutations affecting lymphocyte development and is clinically significant due to the high risk of life-threatening infections. Accurate coding with ICD-10 Code D81.0 is essential for proper diagnosis, documentation, medical billing, and public health reporting.
ICD-10 Code D81.0 represents Severe combined immunodeficiency with reticular dysgenesis, a condition resulting from genetic defects that impair the immune system's ability to fight infections. This code should be used in clinical documentation and billing when diagnosing patients with this severe immunodeficiency, ensuring appropriate treatment and management strategies are implemented.
Severe combined immunodeficiency with reticular dysgenesis is primarily caused by genetic mutations that disrupt the development of immune cells, leading to a profound deficiency in both T and B lymphocytes. This condition progresses rapidly, resulting in increased susceptibility to infections and necessitating immediate medical intervention.
ICD-10 Code D81.0 is utilized in SOAP notes to document the clinical presentation, assessment, and treatment of patients with Severe combined immunodeficiency with reticular dysgenesis. This code aids in capturing the severity of the condition and supports appropriate management in both acute and chronic care settings.
In SOAP notes, ICD-10 Code D81.0 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Severe combined immunodeficiency with reticular dysgenesis. This ensures continuity of care, supports accurate billing, and meets EHR documentation standards.
Severe combined immunodeficiency with reticular dysgenesis requires urgent medical attention, often necessitating hospitalization for management.


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Learn moreICD-10 Code D81.0 is critical in medical billing, particularly in hospital, emergency room, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 99223 | Initial hospital care, typically involving a detailed history and examination. |
| 36415 | Collection of venous blood by venipuncture. |
| 85025 | Complete blood count with differential. |
Common Questions About Using ICD-10 Code D81.0 for Severe combined immunodeficiency with reticular dysgenesis
What are the common symptoms of Severe combined immunodeficiency with reticular dysgenesis?
Common symptoms include recurrent infections, failure to thrive, and chronic diarrhea. Patients may also present with skin infections and respiratory issues due to the lack of functional immune cells.
How is Severe combined immunodeficiency with reticular dysgenesis diagnosed?
Diagnosis is typically made through blood tests showing absent T and B lymphocytes, along with clinical history of recurrent infections and supportive laboratory findings.
What treatment options are available for this condition?
Treatment includes broad-spectrum antibiotics, intravenous immunoglobulin (IVIG) therapy, and strict infection control measures. Bone marrow transplantation may also be considered.
Is Severe combined immunodeficiency with reticular dysgenesis hereditary?
Yes, this condition is usually inherited in an autosomal recessive pattern, meaning both parents must carry the gene mutation for a child to be affected.
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