Cytokine release syndrome, grade 1, is a mild inflammatory response characterized by the release of cytokines into the bloodstream, often triggered by certain therapies such as immunotherapy or infections. This condition is clinically significant as it can progress to more severe forms if not monitored. The ICD-10 Code D89.831 facilitates accurate diagnosis, documentation, medical billing, and public health reporting, ensuring appropriate management and resource allocation.
ICD-10 Code D89.831 represents Cytokine release syndrome, grade 1, which is a mild form of cytokine release syndrome typically associated with certain medical treatments or infections. This code should be used in clinical documentation and billing when a patient exhibits mild symptoms of cytokine release syndrome, allowing for proper tracking and management of the condition.
Cytokine release syndrome, grade 1, is primarily caused by the activation of the immune system, often in response to therapies such as monoclonal antibodies or CAR T-cell therapy. It can progress if not adequately addressed, necessitating medical attention to prevent complications.
In SOAP notes, ICD-10 Code D89.831 is utilized to document the presence of mild cytokine release syndrome. It aids in capturing symptoms, assessments, and treatment plans, relevant in both acute and chronic care settings.
ICD-10 Code D89.831 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of mild cytokine release syndrome, ensuring continuity of care, supporting billing, and meeting EHR documentation standards.
Cytokine release syndrome, grade 1, may require hospitalization for monitoring and treatment. Management focuses on supportive care and addressing underlying causes.


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Learn moreICD-10 Code D89.831 is crucial for billing in hospital, ER, or infectious disease care settings, ensuring accurate reimbursement and compliance.
| CPT Code | Description |
|---|---|
| 99221 | Initial hospital care, typically 30-74 minutes. |
| 96360 | Intravenous infusion, hydration, initial 31 minutes or more. |
| 36415 | Collection of venous blood by venipuncture. |
Common Questions About Using ICD-10 Code D89.831 for Cytokine release syndrome, grade 1
What are the common symptoms of Cytokine release syndrome, grade 1?
Common symptoms include mild fever, chills, fatigue, nausea, and hypotension. These symptoms typically arise after certain treatments or infections and require monitoring.
When should ICD-10 Code D89.831 be used?
This code should be used when a patient presents with mild symptoms of cytokine release syndrome, particularly following immunotherapy or related treatments.
How does Cytokine release syndrome, grade 1 differ from higher grades?
Grade 1 is characterized by mild symptoms without significant organ dysfunction, while higher grades involve more severe symptoms and potential complications requiring intensive management.
Is hospitalization necessary for Cytokine release syndrome, grade 1?
Hospitalization may be required for monitoring, especially if symptoms worsen or if the patient has underlying health conditions that could complicate management.
Clinical Notes
SOAP notes
DAP notes
AI medical notes