Refractory anemia, unspecified, is a type of anemia characterized by the failure of the bone marrow to produce adequate red blood cells despite the presence of normal or increased erythropoietin levels. This condition is clinically significant as it can lead to severe fatigue, weakness, and increased risk of infections. Accurate coding with ICD-10 Code D46.4 is essential for proper diagnosis, documentation, medical billing, and public health reporting, ensuring that patients receive appropriate care and resources.
ICD-10 Code D46.4 represents Refractory anemia, unspecified, which is a form of anemia that does not respond to standard treatments. This condition may arise from various underlying causes, including bone marrow disorders or chronic diseases. The code should be used in clinical documentation and billing when a patient presents with anemia that is resistant to treatment, ensuring accurate representation of the patient's health status.
Refractory anemia, unspecified, is a hematological condition where the bone marrow fails to produce sufficient red blood cells, leading to persistent anemia. This condition can progress to more severe forms of anemia and requires medical intervention to manage symptoms and prevent complications.
In SOAP notes, ICD-10 Code D46.4 is utilized to document the patient's symptoms, assessment findings, and treatment plans related to refractory anemia. This code is relevant in both acute and chronic care settings, facilitating clear communication among healthcare providers and ensuring comprehensive patient management.
ICD-10 Code D46.4 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of refractory anemia. This code is crucial for ensuring continuity of care, supporting accurate billing, and meeting electronic health record documentation standards.
Refractory anemia, unspecified, necessitates prompt medical attention to manage symptoms and prevent complications. Treatment approaches may vary based on the underlying cause.


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Learn moreICD-10 Code D46.4 is critical in medical billing, particularly in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 36430 | Transfusion of red blood cells. |
| 85025 | Complete blood count (CBC) with differential. |
| 85027 | Reticulocyte count. |
| 88305 | Pathology examination of bone marrow biopsy. |
Common Questions About Using ICD-10 Code D46.4 for Refractory anemia, unspecified
What are the common symptoms of refractory anemia?
Common symptoms include persistent fatigue, weakness, pallor, and shortness of breath. Patients may also experience increased susceptibility to infections due to low red blood cell counts.
How is refractory anemia diagnosed?
Diagnosis typically involves a complete blood count (CBC), reticulocyte count, and bone marrow biopsy to assess red blood cell production and rule out other conditions.
What treatments are available for refractory anemia?
Treatment options may include red blood cell transfusions, erythropoiesis-stimulating agents, and supportive care to manage symptoms and prevent complications.
Is refractory anemia a serious condition?
Yes, refractory anemia can lead to significant health complications if not managed properly, including severe fatigue and increased risk of infections.
Clinical Notes
SOAP notes
DAP notes
AI medical notes