Refractory anemia without ring sideroblasts is a type of anemia characterized by ineffective hematopoiesis and a failure to respond to standard treatments. It is clinically significant as it can lead to severe fatigue, weakness, and increased risk of complications. The ICD-10 Code D46.0 facilitates accurate diagnosis, documentation, medical billing, and public health reporting, ensuring that healthcare providers can effectively manage and track this condition.
ICD-10 Code D46.0 represents Refractory anemia without ring sideroblasts, a hematological disorder where the bone marrow fails to produce adequate red blood cells despite normal or increased erythropoietin levels. This code is used in clinical documentation and billing when diagnosing patients who exhibit symptoms of anemia that do not respond to conventional treatments, allowing for appropriate management and resource allocation.
Refractory anemia without ring sideroblasts is primarily caused by intrinsic bone marrow abnormalities leading to ineffective erythropoiesis. The condition can progress to more severe forms of anemia and requires prompt medical attention to prevent complications.
ICD-10 Code D46.0 is utilized in SOAP notes to document the patient's symptoms, assessment findings, and treatment plans. It is relevant in both acute and chronic care settings, ensuring comprehensive documentation of the patient's condition and guiding clinical decision-making.
In SOAP notes, ICD-10 Code D46.0 connects subjective patient-reported symptoms with objective clinical findings, leading to a formal diagnosis. This code is essential for ensuring continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Refractory anemia without ring sideroblasts requires careful management to address symptoms and prevent complications.


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| CPT Code | Description |
|---|---|
| 36430 | Transfusion of red blood cells. |
| 85025 | Complete blood count with automated differential. |
| 85027 | Complete blood count with manual differential. |
| 88305 | Pathology examination of bone marrow. |
Common Questions About Using ICD-10 Code D46.0 for Refractory anemia without ring sideroblasts, so stated
What are the common symptoms of refractory anemia without ring sideroblasts?
Common symptoms include persistent fatigue, weakness, pallor, and shortness of breath. Patients may also experience increased susceptibility to infections and bleeding due to low blood cell counts.
How is refractory anemia without ring sideroblasts diagnosed?
Diagnosis typically involves a complete blood count (CBC), bone marrow biopsy, and exclusion of other causes of anemia. The presence of dysplastic changes in the bone marrow without ring sideroblasts is a key diagnostic feature.
What treatment options are available for refractory anemia without ring sideroblasts?
Treatment may include red blood cell transfusions, erythropoiesis-stimulating agents, and supportive care measures. Management is tailored to the severity of anemia and patient-specific factors.
Is refractory anemia without ring sideroblasts a chronic condition?
Yes, refractory anemia without ring sideroblasts is often a chronic condition that requires ongoing management and monitoring to prevent complications and improve quality of life.
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