Acute megakaryoblastic leukemia, in relapse is a hematological malignancy characterized by the proliferation of megakaryoblasts in the bone marrow. This condition is clinically significant as it often presents with severe thrombocytopenia, leading to increased bleeding risk. Accurate coding with ICD-10 Code C94.22 is essential for proper diagnosis, documentation, medical billing, and public health reporting, ensuring that healthcare providers can effectively manage and treat affected patients.
ICD-10 Code C94.22 represents Acute megakaryoblastic leukemia, in relapse, a subtype of acute myeloid leukemia characterized by the presence of immature megakaryocytes in the bone marrow. This code should be used when documenting a relapse of the disease, indicating a return of symptoms after a period of remission. Proper use of this code in clinical documentation and billing is crucial for accurate patient care and reimbursement.
Acute megakaryoblastic leukemia, in relapse, is caused by genetic mutations leading to the uncontrolled proliferation of megakaryoblasts. The condition can progress rapidly, resulting in severe complications such as bleeding and infection, necessitating immediate medical intervention.
ICD-10 Code C94.22 is utilized in SOAP notes to document the patient's symptoms, assessment findings, and treatment plans. This code is relevant in both acute and chronic care settings, ensuring comprehensive documentation of the patient's condition and facilitating appropriate management strategies.
In SOAP notes, ICD-10 Code C94.22 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Acute megakaryoblastic leukemia, in relapse. This ensures continuity of care, supports accurate billing, and meets EHR documentation standards.
Acute megakaryoblastic leukemia, in relapse, requires urgent medical treatment, often necessitating hospitalization for intensive care.


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| CPT Code | Description |
|---|---|
| 85027 | Complete blood count with differential. |
| 85041 | Platelet count. |
| 38221 | Bone marrow aspiration and/or biopsy. |
| 96413 | Chemotherapy administration, intravenous. |
Common Questions About Using ICD-10 Code C94.22 for Acute megakaryoblastic leukemia, in relapse
What are the common symptoms of Acute megakaryoblastic leukemia, in relapse?
Common symptoms include fatigue, easy bruising, bleeding tendencies, fever, and pallor. Patients may also experience recurrent infections due to bone marrow failure.
How is Acute megakaryoblastic leukemia, in relapse treated?
Treatment typically involves intensive chemotherapy, supportive care such as transfusions, and possibly stem cell transplantation, depending on the patient's condition and response to therapy.
What is the importance of accurate coding for C94.22?
Accurate coding with C94.22 is essential for proper diagnosis, treatment planning, reimbursement, and public health reporting, ensuring that patients receive appropriate care.
When should ICD-10 Code C94.22 be used?
ICD-10 Code C94.22 should be used when documenting a relapse of Acute megakaryoblastic leukemia, indicating a return of symptoms after a period of remission.
Clinical Notes
SOAP notes
DAP notes
AI medical notes