Myxedema coma is a severe, life-threatening condition resulting from untreated hypothyroidism, characterized by a significant decrease in thyroid hormone levels. It is clinically important due to its high mortality rate if not promptly recognized and treated. The ICD-10 Code E03.5 facilitates accurate diagnosis, documentation, medical billing, and public health reporting, ensuring that healthcare providers can effectively manage and track this critical condition.
ICD-10 Code E03.5 represents Myxedema coma, a critical complication of hypothyroidism. This condition arises when there is a severe deficiency of thyroid hormones, leading to a state of metabolic crisis. This code should be used in clinical documentation and billing when a patient presents with symptoms indicative of Myxedema coma, ensuring proper treatment and reimbursement for the healthcare services provided.
Myxedema coma is primarily caused by prolonged, untreated hypothyroidism, often precipitated by factors such as infection, cold exposure, or medication noncompliance. The condition progresses rapidly, leading to altered mental status, hypothermia, and multi-organ failure, necessitating immediate medical intervention.
In SOAP notes, ICD-10 Code E03.5 is utilized to document the diagnosis of Myxedema coma, capturing the patient's symptoms, assessment findings, and treatment plan. This code is relevant in both acute and chronic care settings, ensuring comprehensive documentation of the patient's condition and facilitating appropriate management.
ICD-10 Code E03.5 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Myxedema coma. This code is essential for ensuring continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Myxedema coma requires urgent hospitalization and aggressive treatment to restore thyroid hormone levels and stabilize the patient.


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| CPT Code | Description |
|---|---|
| 99285 | Emergency department visit for high severity. |
| 36415 | Collection of venous blood by venipuncture. |
| 84443 | Thyroid stimulating hormone (TSH) test. |
Common Questions About Using ICD-10 Code E03.5 for Myxedema coma
What are the common symptoms of Myxedema coma?
Common symptoms include severe lethargy, confusion, hypothermia, bradycardia, and significant edema. Patients may also present with respiratory failure and altered mental status.
How is Myxedema coma treated?
Treatment involves immediate intravenous administration of levothyroxine, supportive care to manage symptoms, and monitoring for complications. Hospitalization is often required.
When should ICD-10 Code E03.5 be used?
ICD-10 Code E03.5 should be used when a patient presents with severe symptoms of hypothyroidism indicative of Myxedema coma, ensuring accurate diagnosis and billing.
What is the prognosis for patients with Myxedema coma?
The prognosis can be poor if not treated promptly, with high mortality rates. However, with immediate and appropriate treatment, many patients can recover.
Clinical Notes
SOAP notes
DAP notes
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