Autoimmune lymphoproliferative syndrome (ALPS) is a rare genetic disorder characterized by the abnormal proliferation of lymphocytes due to defective apoptosis. This condition can lead to lymphadenopathy, splenomegaly, and autoimmune manifestations. Accurate coding with ICD-10 Code D89.82 is essential for proper diagnosis, documentation, medical billing, and public health reporting, ensuring that patients receive appropriate care and resources.
ICD-10 Code D89.82 represents Autoimmune lymphoproliferative syndrome (ALPS), a disorder resulting from mutations affecting lymphocyte apoptosis. This code should be used in clinical documentation and billing when diagnosing patients with ALPS, particularly when they present with symptoms such as lymphadenopathy, splenomegaly, and autoimmune complications.
Autoimmune lymphoproliferative syndrome (ALPS) is primarily caused by genetic mutations that impair the normal process of programmed cell death (apoptosis), leading to an accumulation of lymphocytes. This condition can progress to severe autoimmune disorders and requires prompt medical attention to manage symptoms and prevent complications.
ICD-10 Code D89.82 is utilized in SOAP notes to document the presence of Autoimmune lymphoproliferative syndrome (ALPS). It plays a crucial role in capturing patient symptoms, assessments, and treatment plans, relevant in both acute and chronic care settings.
In SOAP notes, ICD-10 Code D89.82 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Autoimmune lymphoproliferative syndrome (ALPS). This ensures continuity of care, supports accurate billing, and meets EHR documentation standards.
Management of Autoimmune lymphoproliferative syndrome (ALPS) often requires hospitalization due to potential complications. Treatment focuses on controlling symptoms and preventing autoimmune manifestations.


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Learn moreICD-10 Code D89.82 is critical for billing purposes in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 99214 | Established patient office visit, moderate complexity. |
| 85025 | Complete blood count with differential. |
| 36415 | Collection of venous blood by venipuncture. |
Common Questions About Using ICD-10 Code D89.82 for Autoimmune lymphoproliferative syndrome [ALPS]
What are the common symptoms of ALPS?
Common symptoms of Autoimmune lymphoproliferative syndrome (ALPS) include swollen lymph nodes, an enlarged spleen, fatigue, and recurrent infections due to immune dysregulation.
How is ALPS diagnosed?
ALPS is diagnosed through clinical evaluation, family history assessment, and laboratory tests that show elevated lymphocyte counts and autoimmune manifestations.
What treatments are available for ALPS?
Treatment for ALPS may include corticosteroids, immunosuppressive therapy, and supportive care to manage symptoms and prevent complications.
Is ALPS a hereditary condition?
Yes, Autoimmune lymphoproliferative syndrome (ALPS) is often hereditary, typically caused by mutations in genes involved in lymphocyte apoptosis.
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