Monoclonal mast cell activation syndrome is a disorder characterized by the abnormal proliferation and activation of mast cells, leading to a range of symptoms including allergic reactions, anaphylaxis, and other systemic manifestations. Accurate coding with ICD-10 Code D89.41 is essential for proper diagnosis, documentation, medical billing, and public health reporting, ensuring that patients receive appropriate care and that healthcare providers are reimbursed for their services.
ICD-10 Code D89.41 represents Monoclonal mast cell activation syndrome, a condition resulting from the excessive activation of mast cells due to monoclonal proliferation. This code should be used in clinical documentation and billing when diagnosing patients exhibiting symptoms related to mast cell activation, ensuring accurate representation of the patient's condition for treatment and reimbursement purposes.
Monoclonal mast cell activation syndrome is caused by the abnormal growth of mast cells, which can lead to severe allergic reactions and systemic symptoms. The condition requires medical attention due to its potential for serious complications, including anaphylaxis. Early diagnosis and management are crucial for patient safety.
ICD-10 Code D89.41 is utilized in SOAP notes to document the patient's symptoms, assessment, and treatment plan. It is relevant in both acute and chronic care settings, facilitating clear communication among healthcare providers and ensuring comprehensive patient care.
In SOAP notes, ICD-10 Code D89.41 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Monoclonal mast cell activation syndrome. This ensures continuity of care, supports accurate billing, and meets EHR documentation standards.
Monoclonal mast cell activation syndrome may require hospitalization for severe cases. Treatment focuses on managing symptoms and preventing complications.


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Learn moreICD-10 Code D89.41 is critical in medical billing, particularly in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 99213 | Established patient office visit, low complexity. |
| 85025 | Complete blood count with differential. |
| 95004 | Allergy testing, percutaneous. |
| 94640 | Inhalation treatment for respiratory conditions. |
Common Questions About Using ICD-10 Code D89.41 for Monoclonal mast cell activation syndrome
What are the common symptoms of Monoclonal mast cell activation syndrome?
Common symptoms include recurrent anaphylaxis, flushing, urticaria, gastrointestinal distress, and systemic reactions due to mast cell mediator release.
How is Monoclonal mast cell activation syndrome diagnosed?
Diagnosis is based on clinical history, symptom presentation, and may include laboratory tests to assess mast cell activation and proliferation.
What treatments are available for Monoclonal mast cell activation syndrome?
Treatment typically involves antihistamines, corticosteroids, and epinephrine for severe reactions, along with patient education on trigger avoidance.
Is Monoclonal mast cell activation syndrome a chronic condition?
Yes, it can be a chronic condition requiring ongoing management and monitoring to prevent severe allergic reactions and complications.
Clinical Notes
SOAP notes
DAP notes
AI medical notes