ICD-10 Code D82.4 | Hyperimmunoglobulin E [IgE] syndrome Symptoms, Diagnosis, Billing

Hyperimmunoglobulin E [IgE] syndrome is a rare immunodeficiency disorder characterized by elevated levels of IgE antibodies, leading to recurrent infections, eczema, and allergic manifestations. The condition is often caused by genetic mutations affecting immune regulation. Accurate coding with ICD-10 Code D82.4 is essential for proper diagnosis, documentation, billing, and public health reporting, ensuring that patients receive appropriate care and resources.

What is ICD-10 Code D82.4 for Hyperimmunoglobulin E [IgE] syndrome?

ICD-10 Code D82.4 represents Hyperimmunoglobulin E [IgE] syndrome, a condition marked by significantly elevated IgE levels and a predisposition to infections and allergic reactions. This code should be used in clinical documentation and billing when diagnosing patients with this syndrome, ensuring accurate representation of the patient's health status and facilitating appropriate treatment.

ICD-10 Code D82.4 – Clinical Definition and Explanation of Hyperimmunoglobulin E [IgE] syndrome

Hyperimmunoglobulin E [IgE] syndrome is primarily caused by genetic mutations that impair the immune system's ability to respond to infections and allergens. Patients often experience recurrent skin infections, respiratory issues, and severe allergic reactions, necessitating medical attention for management and treatment.

Key Clinical Features:

• Elevated serum IgE levels, often exceeding 2000 IU/mL.
• Recurrent skin infections, particularly Staphylococcus aureus.
• Severe eczema and other allergic manifestations.
• Respiratory complications, including recurrent pneumonia.

ICD-10 Code D82.4 for Hyperimmunoglobulin E [IgE] syndrome – SOAP Notes & Clinical Use

ICD-10 Code D82.4 is utilized in SOAP notes to document the patient's symptoms, assessment findings, and treatment plans. This code is relevant in both acute and chronic care settings, ensuring comprehensive documentation of the patient's condition and guiding clinical decision-making.

What Does ICD-10 Code D82.4 for Hyperimmunoglobulin E [IgE] syndrome Mean in SOAP Notes?

In SOAP notes, ICD-10 Code D82.4 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Hyperimmunoglobulin E [IgE] syndrome. This coding ensures continuity of care, supports accurate billing, and meets EHR documentation standards.

Treatment Options for ICD-10 Code D82.4 – Hyperimmunoglobulin E [IgE] syndrome

Management of Hyperimmunoglobulin E [IgE] syndrome often requires a multidisciplinary approach, including pharmacologic and supportive care.

Antibiotic Therapy:

• First-line: Cephalexin 500 mg orally every 6 hours for 10 days.
• Alternative: Clindamycin 300 mg orally every 6 hours for 10 days.
• Duration: Typically 10-14 days depending on infection severity.

Supportive Care:

• Regular monitoring of IgE levels and immune function.
• Management of eczema with topical corticosteroids.
• Education on avoiding known allergens and triggers.

Infection Control:

• Strict hygiene practices to prevent skin infections.
• Isolation precautions during acute infections.
• Vaccination updates as per immunization guidelines.

How to Document Symptoms of Hyperimmunoglobulin E [IgE] syndrome (ICD-10 D82.4) in SOAP Notes

Subjective:

• Patient reports recurrent skin infections and eczema flare-ups.
• History of frequent respiratory infections requiring antibiotics.
• Family history of allergic conditions and immunodeficiency.

Objective:

• Elevated serum IgE levels noted at 2500 IU/mL.
• Skin examination reveals extensive eczema and crusted lesions.
• Lung auscultation shows wheezing and decreased breath sounds.

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SOAP Note Guidelines for Diagnosing Hyperimmunoglobulin E [IgE] syndrome (ICD-10 Code D82.4)

Assessment:

• Diagnosis: Hyperimmunoglobulin E [IgE] syndrome, moderate severity.
• ICD-10 Code: D82.4.
• Triggers: Recurrent infections and environmental allergens.

Plan:

• Initiate antibiotic therapy as per infection control guidelines.
• Educate patient on skin care and allergen avoidance.
• Schedule follow-up in 4 weeks to monitor IgE levels and treatment response.

Treatment & Plan Section for ICD-10 Code D82.4 – Hyperimmunoglobulin E [IgE] syndrome

• First-line pharmacologic treatments include antibiotics for infections.
• Non-pharmacologic strategies involve skin care and allergen avoidance.
• Monitoring includes regular IgE level assessments and infection tracking.
• Follow-up visits should be scheduled to evaluate treatment efficacy.

Using ICD-10 Code D82.4 for Hyperimmunoglobulin E [IgE] syndrome in Billing & SOAP Note Compliance

• Select appropriate subcodes based on clinical severity or complications.
• Document symptoms clearly under Subjective (S) and Objective (O) in SOAP notes.
• Ensure treatment plans align with clinical guidelines to support justified billing.
• Commonly billed CPT codes include those for office visits and laboratory tests.

Related ICD-10 Codes Often Used with Hyperimmunoglobulin E [IgE] syndrome

• D82.0 – Hyperimmunoglobulin E syndrome due to DOCK8 deficiency
• D82.1 – Hyperimmunoglobulin E syndrome due to STAT3 deficiency
• D80.9 – Immunodeficiency, unspecified

ICD-10 Code D82.4 in Medical Billing and Insurance for Hyperimmunoglobulin E [IgE] syndrome

ICD-10 Code D82.4 is crucial for accurate billing in hospital, ER, or infectious disease care settings.

Billing Notes:

• Ensure thorough documentation of patient history and clinical findings.
• Use the code in conjunction with relevant CPT codes for comprehensive billing.
• Highlight key chart elements such as IgE levels and infection history.

Common CPT Pairings: