ICD-10 Code D81.82 | Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] Symptoms, Diagnosis, Billing

Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] is a primary immunodeficiency disorder caused by mutations in the PIK3CD gene, leading to dysregulated immune responses. Clinically significant due to its association with increased susceptibility to infections, autoimmune diseases, and malignancies, accurate coding with ICD-10 Code D81.82 is essential for proper diagnosis, documentation, billing, and public health reporting.

What is ICD-10 Code D81.82 for Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]?

ICD-10 Code D81.82 represents Activated Phosphoinositide 3-kinase Delta Syndrome [APDS], a genetic disorder characterized by immune dysregulation. This code should be used when documenting cases of APDS in clinical settings, ensuring accurate representation of the condition for billing and treatment planning.

ICD-10 Code D81.82 – Clinical Definition and Explanation of Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] is caused by gain-of-function mutations in the PIK3CD gene, leading to abnormal activation of the phosphoinositide 3-kinase pathway. This condition progresses with increased susceptibility to infections and autoimmune manifestations, necessitating prompt medical attention.

Key Clinical Features:

• Recurrent bacterial, viral, and fungal infections
• Autoimmune disorders such as lupus or rheumatoid arthritis
• Lymphoproliferative disorders
• Failure to thrive in pediatric patients

ICD-10 Code D81.82 for Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] – SOAP Notes & Clinical Use

ICD-10 Code D81.82 is utilized in SOAP notes to document the clinical presentation, assessment, and treatment of patients with Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]. This code aids in capturing both acute and chronic care needs, ensuring comprehensive patient management.

What Does ICD-10 Code D81.82 for Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] Mean in SOAP Notes?

In SOAP notes, ICD-10 Code D81.82 connects subjective patient reports and objective clinical findings to a formal diagnosis of Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]. This ensures continuity of care, supports accurate billing, and meets EHR documentation standards.

Treatment Options for ICD-10 Code D81.82 – Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] requires a multidisciplinary approach for management, including immunotherapy and supportive care.

Antibiotic Therapy:

• Not applicable as APDS is not an infectious disease requiring antibiotics.

Supportive Care:

• Immunoglobulin replacement therapy for recurrent infections
• Management of autoimmune manifestations
• Regular monitoring for malignancies

Infection Control:

• Standard precautions to prevent infections
• Vaccination updates as per immunization guidelines

How to Document Symptoms of Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] (ICD-10 D81.82) in SOAP Notes

Subjective:

• Patient reports recurrent infections requiring hospitalization.
• History of autoimmune symptoms such as joint pain and fatigue.
• Family history of immunodeficiency disorders.
• Patient expresses concern about frequent illnesses.

Objective:

• Vital signs: stable, afebrile.
• Physical exam: lymphadenopathy noted.
• Laboratory findings: low immunoglobulin levels.
• Imaging: no acute abnormalities on chest X-ray.

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SOAP Note Guidelines for Diagnosing Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] (ICD-10 Code D81.82)

Assessment:

• Activated Phosphoinositide 3-kinase Delta Syndrome [APDS], moderate severity.
• ICD-10 Code D81.82.
• Triggers include recurrent infections and autoimmune flare-ups.

Plan:

• Initiate immunoglobulin replacement therapy.
• Refer to immunology for further evaluation.
• Educate patient on infection prevention strategies.
• Schedule follow-up in 3 months for reassessment.

Treatment & Plan Section for ICD-10 Code D81.82 – Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

• Immunoglobulin replacement therapy to prevent infections.
• Corticosteroids for autoimmune symptoms as needed.
• Regular monitoring of immunoglobulin levels and overall health.
• Patient education on recognizing signs of infection.

Using ICD-10 Code D81.82 for Activated Phosphoinositide 3-kinase Delta Syndrome [APDS] in Billing & SOAP Note Compliance

• Ensure accurate documentation of symptoms and history in Subjective (S) and Objective (O) sections.
• Use D81.82 for all encounters related to APDS to support billing.
• Align treatment plans with clinical guidelines to justify claims.
• Include relevant CPT codes for immunotherapy and follow-up visits.

Related ICD-10 Codes Often Used with Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

• D81.89 – Other Immunodeficiencies
• D83.9 – Common Variable Immunodeficiency, Unspecified
• D84.9 – Immunodeficiency, Unspecified

ICD-10 Code D81.82 in Medical Billing and Insurance for Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]

ICD-10 Code D81.82 is critical in billing for hospital, ER, or infectious disease care related to Activated Phosphoinositide 3-kinase Delta Syndrome [APDS].

Billing Notes:

• Document all relevant patient history and clinical findings to support the use of D81.82.
• Use this code in conjunction with other relevant codes for comprehensive billing.
• Ensure that treatment plans are clearly outlined in the medical record.

Common CPT Pairings: