Myelofibrosis is a rare bone marrow disorder characterized by the replacement of normal bone marrow with fibrous tissue, leading to severe anemia, splenomegaly, and other systemic symptoms. The condition can arise as a primary disorder or secondary to other hematological diseases. Accurate coding with ICD-10 Code D75.81 is essential for proper diagnosis, documentation, medical billing, and public health reporting, ensuring that healthcare providers can effectively manage and treat this complex condition.
ICD-10 Code D75.81 specifically denotes Myelofibrosis, a hematological condition that results in the abnormal proliferation of fibrous tissue in the bone marrow. This code should be utilized in clinical documentation when diagnosing patients with this condition, particularly when there are symptoms of anemia, splenomegaly, or other related complications. Proper use of this code facilitates accurate billing and ensures comprehensive patient care.
Myelofibrosis is primarily caused by genetic mutations affecting hematopoietic stem cells, leading to abnormal blood cell production and fibrosis in the bone marrow. The condition can progress to severe complications, including acute leukemia, necessitating prompt medical attention.
In SOAP notes, ICD-10 Code D75.81 is utilized to document the patient's symptoms, assessment findings, and treatment plans related to Myelofibrosis. This code is relevant in both acute and chronic care settings, ensuring comprehensive documentation of the patient's clinical status.
ICD-10 Code D75.81 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Myelofibrosis. This code is crucial for ensuring continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Myelofibrosis often requires hospitalization for management of severe symptoms and complications. Treatment may include disease-modifying therapies and supportive care.


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Learn moreICD-10 Code D75.81 is critical in billing for Myelofibrosis, particularly in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 85025 | Complete blood count with differential and platelet count |
| 36415 | Collection of venous blood by venipuncture |
| 88305 | Pathology examination of bone marrow biopsy |
Common Questions About Using ICD-10 Code D75.81 for Myelofibrosis
What are the common symptoms of Myelofibrosis?
Common symptoms include fatigue, weakness, splenomegaly, night sweats, and easy bruising. Patients may also experience bone pain and anemia-related symptoms.
How is Myelofibrosis diagnosed?
Diagnosis typically involves a combination of clinical evaluation, blood tests, and a bone marrow biopsy to assess for fibrosis and abnormal cell production.
What treatments are available for Myelofibrosis?
Treatment options include JAK inhibitors, blood transfusions for anemia, and supportive care to manage symptoms and complications.
Is Myelofibrosis a contagious disease?
No, Myelofibrosis is not contagious. It is a bone marrow disorder that arises from genetic mutations and is not transmitted between individuals.
Clinical Notes
SOAP notes
DAP notes
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