Sickle-cell thalassemia beta plus with splenic sequestration is a genetic blood disorder characterized by the presence of both sickle cell disease and beta-thalassemia. This condition leads to abnormal hemoglobin production, resulting in hemolytic anemia, pain crises, and potential splenic sequestration. Accurate coding with ICD-10 Code D57.452 is essential for proper diagnosis, documentation, medical billing, and public health reporting, ensuring that healthcare providers can effectively manage and treat affected patients.
ICD-10 Code D57.452 represents Sickle-cell thalassemia beta plus with splenic sequestration, a condition where patients experience both sickle cell disease and beta-thalassemia, leading to severe anemia and splenic complications. This code should be used in clinical documentation and billing when diagnosing patients with this specific combination of disorders, particularly when splenic sequestration is present.
Sickle-cell thalassemia beta plus with splenic sequestration is caused by mutations in the HBB gene, leading to abnormal hemoglobin production. The condition can progress to severe anemia and splenic sequestration crises, necessitating prompt medical attention to prevent complications such as splenic infarction or infection.
ICD-10 Code D57.452 is utilized in SOAP notes to document the patient's symptoms, assessment findings, and treatment plans. This code is relevant in both acute and chronic care settings, facilitating accurate communication among healthcare providers and ensuring appropriate management of the condition.
In SOAP notes, ICD-10 Code D57.452 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis. This code is crucial for ensuring continuity of care, supporting billing processes, and meeting EHR documentation standards.
Management of Sickle-cell thalassemia beta plus with splenic sequestration often requires hospitalization due to the risk of severe complications. Treatment focuses on symptom relief and preventing further complications.


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Learn moreICD-10 Code D57.452 is critical for accurate billing in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 36430 | Blood transfusion, per unit. |
| 99213 | Established patient office visit, level 3. |
| 85025 | Complete blood count with automated differential. |
Common Questions About Using ICD-10 Code D57.452 for Sickle-cell thalassemia beta plus with splenic sequestration
What are the common symptoms of Sickle-cell thalassemia beta plus with splenic sequestration?
Common symptoms include severe fatigue, pain crises, splenomegaly, and increased susceptibility to infections due to splenic dysfunction.
How is Sickle-cell thalassemia beta plus with splenic sequestration treated?
Treatment typically involves hydration, pain management, blood transfusions, and prophylactic antibiotics to prevent infections.
When should ICD-10 Code D57.452 be used?
This code should be used when diagnosing patients with Sickle-cell thalassemia beta plus specifically with splenic sequestration, particularly during acute episodes.
What is the importance of accurate coding for Sickle-cell thalassemia beta plus?
Accurate coding is essential for proper diagnosis, treatment planning, billing, and public health reporting, ensuring patients receive appropriate care.
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