Sickle-cell thalassemia beta plus with acute chest syndrome is a serious complication of sickle cell disease characterized by the presence of both sickle cell and beta-thalassemia traits. This condition leads to vaso-occlusive crises and acute chest syndrome, which can result in respiratory distress and requires immediate medical intervention. The ICD-10 Code D57.451 facilitates accurate diagnosis, documentation, medical billing, and public health reporting, ensuring that healthcare providers can effectively manage and treat this complex condition.
ICD-10 Code D57.451 represents Sickle-cell thalassemia beta plus with acute chest syndrome, a condition that arises from the combination of sickle cell disease and beta-thalassemia. This code should be used in clinical documentation and billing when a patient presents with acute chest syndrome, which is characterized by chest pain, fever, and respiratory symptoms, necessitating prompt medical evaluation and treatment.
Sickle-cell thalassemia beta plus with acute chest syndrome is caused by the abnormal hemoglobin resulting from both sickle cell and beta-thalassemia mutations. This condition can lead to severe complications, including acute chest syndrome, which requires immediate medical attention due to the risk of respiratory failure. Early recognition and treatment are crucial for improving patient outcomes.
ICD-10 Code D57.451 is utilized in SOAP notes to document the patient's symptoms, assessment findings, and treatment plan for acute chest syndrome. This code is relevant in both acute and chronic care settings, ensuring comprehensive documentation that supports clinical decision-making and billing processes.
In SOAP notes, ICD-10 Code D57.451 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of acute chest syndrome. This code plays a vital role in ensuring continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Sickle-cell thalassemia beta plus with acute chest syndrome often necessitates hospitalization due to the risk of severe respiratory complications. Treatment focuses on managing symptoms and preventing further complications.


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Learn moreICD-10 Code D57.451 is critical in medical billing, particularly in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 99223 | Initial hospital care, typically 70 minutes or more. |
| 36415 | Collection of venous blood by venipuncture. |
| 71045 | Radiologic examination, chest, single view. |
| 96365 | Intravenous infusion, for therapy, prophylaxis, or diagnosis. |
Common Questions About Using ICD-10 Code D57.451 for Sickle-cell thalassemia beta plus with acute chest syndrome
What are the common symptoms of acute chest syndrome?
Common symptoms include chest pain, difficulty breathing, fever, and cough. Patients may also experience hypoxemia and increased respiratory rate, necessitating prompt medical evaluation.
How is acute chest syndrome treated?
Treatment typically involves hospitalization, oxygen therapy, intravenous fluids, and antibiotics to manage infections. Pain management is also crucial to alleviate discomfort.
When should ICD-10 Code D57.451 be used?
This code should be used when a patient with sickle-cell thalassemia beta plus presents with acute chest syndrome, characterized by respiratory symptoms and chest pain.
What is the importance of accurate coding for D57.451?
Accurate coding ensures proper documentation, facilitates appropriate billing, and supports public health reporting, ultimately improving patient care and resource allocation.
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