Castleman disease is a rare lymphoproliferative disorder characterized by the abnormal growth of lymphoid tissue. It can present as unicentric or multicentric forms, with clinical manifestations ranging from localized lymphadenopathy to systemic symptoms such as fever and weight loss. Accurate coding with ICD-10 Code D47.Z2 is essential for proper diagnosis, documentation, medical billing, and public health reporting, ensuring that healthcare providers can effectively manage and treat this complex condition.
ICD-10 Code D47.Z2 represents Castleman disease, a condition involving hyperplastic lymphoid tissue that can lead to significant morbidity. This code should be used when documenting cases of Castleman disease, particularly when distinguishing between unicentric and multicentric forms, to ensure accurate billing and clinical management.
Castleman disease is caused by an abnormal proliferation of lymphoid tissue, often linked to viral infections such as HHV-8. The condition can progress rapidly and may lead to severe complications, necessitating prompt medical attention.
ICD-10 Code D47.Z2 is utilized in SOAP notes to document the clinical presentation, assessment, and treatment of Castleman disease. It plays a crucial role in both acute and chronic care settings, ensuring comprehensive patient management.
In SOAP notes, ICD-10 Code D47.Z2 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Castleman disease. This code is vital for ensuring continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Management of Castleman disease may require hospitalization, especially in severe cases. Treatment approaches vary based on the disease's form and severity.


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Learn moreICD-10 Code D47.Z2 is essential for accurate billing in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 99214 | Established patient office visit, moderate complexity. |
| 85025 | Complete blood count with automated differential. |
| 36415 | Collection of venous blood by venipuncture. |
| 88305 | Pathology examination of tissue, level II. |
Common Questions About Using ICD-10 Code D47.Z2 for Castleman disease
What are the common symptoms of Castleman disease?
Common symptoms include lymphadenopathy, fever, night sweats, and weight loss. Patients may also experience fatigue and malaise, which can significantly impact their quality of life.
How is Castleman disease diagnosed?
Diagnosis typically involves a combination of clinical evaluation, imaging studies, and histopathological examination of lymph nodes. Laboratory tests may also reveal elevated inflammatory markers.
Is Castleman disease contagious?
Castleman disease is not contagious. It is a lymphoproliferative disorder that may be associated with viral infections, but it does not spread from person to person.
What treatment options are available for Castleman disease?
Treatment options vary based on the disease's form and severity, including corticosteroids, immunotherapy, and supportive care. Management should be tailored to the individual patient's needs.
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