Refractory anemia with excess of blasts, unspecified is a hematological condition characterized by ineffective hematopoiesis leading to anemia and an increased number of immature blood cells (blasts) in the bone marrow. This condition is clinically significant as it may progress to acute myeloid leukemia (AML). The ICD-10 Code D46.20 facilitates accurate diagnosis, documentation, medical billing, and public health reporting, ensuring appropriate management and resource allocation.
ICD-10 Code D46.20 represents Refractory anemia with excess of blasts, unspecified, a subtype of myelodysplastic syndromes. This code is used when patients exhibit anemia alongside an increased number of blasts in the bone marrow without a specified subtype. It is essential for clinical documentation and billing to accurately reflect the patient's condition and to ensure appropriate treatment and follow-up.
Refractory anemia with excess of blasts, unspecified is caused by a failure of the bone marrow to produce adequate healthy blood cells, leading to anemia and an accumulation of immature cells. This condition requires medical attention due to its potential progression to more severe forms of leukemia.
ICD-10 Code D46.20 is utilized in SOAP notes to document the patient's symptoms, assessment findings, and treatment plans. It plays a crucial role in both acute and chronic care settings, ensuring comprehensive documentation of the patient's condition and guiding clinical decision-making.
In SOAP notes, ICD-10 Code D46.20 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis. This code is vital for ensuring continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Refractory anemia with excess of blasts, unspecified requires prompt medical intervention to manage symptoms and prevent complications.


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| CPT Code | Description |
|---|---|
| 36430 | Blood transfusion, per unit. |
| 85025 | Complete blood count (CBC) with differential. |
| 85027 | Complete blood count (CBC), automated. |
Common Questions About Using ICD-10 Code D46.20 for Refractory anemia with excess of blasts, unspecified
What are the common symptoms of refractory anemia with excess of blasts?
Common symptoms include fatigue, weakness, pallor, and increased susceptibility to infections due to low blood cell counts.
How is refractory anemia with excess of blasts diagnosed?
Diagnosis is typically made through blood tests showing anemia and a bone marrow biopsy revealing increased blasts.
What treatment options are available for this condition?
Treatment may include blood transfusions, erythropoiesis-stimulating agents, and close monitoring for progression to leukemia.
Is hospitalization required for patients with this condition?
Hospitalization may be necessary for severe cases, especially if there are complications such as infections or significant anemia.
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