Atypical chronic myeloid leukemia (CML) is a hematological malignancy characterized by the presence of myeloid cells in the blood and bone marrow. In cases classified under ICD-10 code C92.20, the BCR/ABL fusion gene is absent, indicating a different pathophysiological mechanism. This condition is clinically significant as it may not respond to standard CML therapies, necessitating accurate documentation for appropriate treatment planning, billing, and public health reporting.
ICD-10 code C92.20 represents atypical chronic myeloid leukemia that is negative for the BCR/ABL fusion gene and has not achieved remission. This code is used when documenting cases where patients exhibit chronic myeloid leukemia symptoms without the typical genetic markers, which is crucial for guiding treatment decisions and ensuring accurate billing and coding practices.
Atypical chronic myeloid leukemia, BCR/ABL-negative, is a rare form of leukemia that does not respond to standard therapies used for typical CML. It may arise due to various genetic mutations and requires specialized treatment approaches. Early diagnosis and intervention are critical to managing the disease effectively.
In clinical workflows, ICD-10 code C92.20 is utilized in SOAP notes to document the patient's symptoms, assessment findings, and treatment plans. This code is essential for both acute and chronic care settings, ensuring that healthcare providers can track disease progression and treatment efficacy.
ICD-10 code C92.20 connects subjective patient reports and objective clinical findings to a formal diagnosis of atypical chronic myeloid leukemia. This code is vital for maintaining continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Management of atypical chronic myeloid leukemia requires urgent medical attention and may involve hospitalization for intensive treatment.


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Learn moreICD-10 code C92.20 is critical for accurate billing in hospital, emergency room, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 85025 | Complete blood count with differential. |
| 38221 | Bone marrow aspiration and/or biopsy. |
| 96413 | Chemotherapy administration, intravenous, push. |
| 99214 | Established patient office visit, moderate complexity. |
Common Questions About Using ICD-10 Code C92.20 for Atyp chronic myeloid leuk, BCR/ABL-neg, not achieve remis
What are the common symptoms of atypical chronic myeloid leukemia?
Common symptoms include fatigue, unexplained weight loss, night sweats, and increased bruising or bleeding. Patients may also experience splenomegaly and leukocytosis.
How is atypical chronic myeloid leukemia diagnosed?
Diagnosis is made through blood tests showing elevated myeloid cells, bone marrow biopsy, and genetic testing to confirm the absence of the BCR/ABL fusion gene.
What treatment options are available for this condition?
Treatment may include targeted therapies based on genetic mutations, supportive care for symptoms, and potential enrollment in clinical trials for novel therapies.
Why is accurate coding important for atypical chronic myeloid leukemia?
Accurate coding ensures appropriate treatment planning, facilitates billing and reimbursement, and supports public health reporting for this rare condition.
Clinical Notes
SOAP notes
DAP notes
AI medical notes