Chronic myeloid leukemia (CML) is a hematological malignancy characterized by the overproduction of myeloid cells in the bone marrow. The BCR/ABL fusion gene, resulting from a translocation between chromosomes 9 and 22, is a hallmark of this condition. In relapse, patients experience a return of symptoms after a period of remission, necessitating accurate coding with ICD-10 Code C92.12 for effective diagnosis, documentation, billing, and public health reporting.
ICD-10 Code C92.12 specifically denotes chronic myeloid leukemia that is BCR/ABL-positive and in a state of relapse. This code is utilized when a patient previously diagnosed with CML experiences a resurgence of the disease after treatment. Accurate use of this code in clinical documentation and billing is essential for tracking disease progression and ensuring appropriate reimbursement for healthcare services.
Chronic myeloid leukemia, BCR/ABL-positive, in relapse occurs when the disease re-emerges after a period of treatment-induced remission. The underlying cause is the presence of the BCR/ABL fusion gene, which leads to uncontrolled proliferation of myeloid cells. This condition requires prompt medical intervention due to its potential for progression to acute phases.
ICD-10 Code C92.12 is integral to SOAP notes, facilitating the documentation of patient symptoms, assessments, and treatment plans. This code is relevant in both acute and chronic care settings, ensuring that healthcare providers accurately capture the patient's clinical status and treatment response.
In SOAP notes, ICD-10 Code C92.12 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of chronic myeloid leukemia in relapse. This code is crucial for ensuring continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Management of chronic myeloid leukemia, BCR/ABL-positive, in relapse often necessitates hospitalization for intensive treatment. Targeted therapies and supportive care are critical in managing symptoms and preventing complications.


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Learn moreICD-10 Code C92.12 is critical for accurate billing in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 99214 | Established patient office visit, moderate complexity. |
| 85025 | Complete blood count with differential. |
| 36415 | Collection of venous blood by venipuncture. |
| 88305 | Pathology examination of tissue, including bone marrow. |
Common Questions About Using ICD-10 Code C92.12 for Chronic myeloid leukemia, BCR/ABL-positive, in relapse
What are the common symptoms of chronic myeloid leukemia in relapse?
Common symptoms include fatigue, night sweats, unexplained weight loss, and splenomegaly. Patients may also report recurrent infections due to compromised immunity.
How is chronic myeloid leukemia diagnosed?
Diagnosis typically involves blood tests showing elevated white blood cell counts, bone marrow biopsy, and cytogenetic analysis to detect the BCR/ABL fusion gene.
What treatments are available for chronic myeloid leukemia in relapse?
Treatment options include targeted therapies such as Imatinib, Dasatinib, or Nilotinib, along with supportive care to manage symptoms and complications.
How does ICD-10 Code C92.12 impact billing?
ICD-10 Code C92.12 is essential for accurate billing, ensuring that healthcare providers are reimbursed for services related to the management of chronic myeloid leukemia in relapse.
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