Hairy cell leukemia, in relapse is a hematological malignancy characterized by the proliferation of atypical B lymphocytes with hairy projections. This condition is clinically significant as it indicates a return of the disease after a period of remission, necessitating prompt medical intervention. The ICD-10 Code C91.42 facilitates accurate diagnosis, documentation, medical billing, and public health reporting, ensuring that healthcare providers can effectively track and manage patient care.
ICD-10 Code C91.42 specifically denotes Hairy cell leukemia that has relapsed after treatment. This condition arises from the malignant transformation of B lymphocytes, leading to splenomegaly, cytopenias, and increased susceptibility to infections. This code should be used in clinical documentation and billing when a patient presents with signs of relapse, ensuring appropriate treatment and follow-up.
Hairy cell leukemia, in relapse occurs when previously treated patients experience a resurgence of the disease, often after a period of remission. The condition requires immediate medical attention due to its potential complications and impact on the patient's health. Relapse may be indicated by worsening symptoms or laboratory findings.
In SOAP notes, ICD-10 Code C91.42 is utilized to document the patient's symptoms, assessment findings, and treatment plans related to the relapse of Hairy cell leukemia. This code is essential for both acute and chronic care settings, ensuring comprehensive patient management and accurate billing.
ICD-10 Code C91.42 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Hairy cell leukemia in relapse. This code is crucial for ensuring continuity of care, supporting billing processes, and meeting EHR documentation standards.
The management of Hairy cell leukemia, in relapse often necessitates hospitalization for intensive treatment. Therapeutic approaches may include chemotherapy and supportive care to manage symptoms and prevent complications.


HIPAA-compliant and designed with privacy in mind, your patient’s data is protected. Focus on care while we safeguard your information.
Learn moreICD-10 Code C91.42 is critical in medical billing, particularly in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 96413 | Chemotherapy administration, intravenous, push technique. |
| 36415 | Collection of venous blood by venipuncture. |
| 85025 | Complete blood count with automated differential. |
Common Questions About Using ICD-10 Code C91.42 for Hairy cell leukemia, in relapse
What are the common symptoms of Hairy cell leukemia in relapse?
Common symptoms include fatigue, recurrent infections, splenomegaly, and weight loss. Patients may also experience night sweats and lymphadenopathy, indicating disease progression.
How is Hairy cell leukemia in relapse treated?
Treatment typically involves chemotherapy with agents like Cladribine or Pentostatin. Supportive care, including transfusions and antibiotics, may also be necessary to manage symptoms and prevent complications.
When should ICD-10 Code C91.42 be used?
ICD-10 Code C91.42 should be used when a patient presents with signs and symptoms indicative of a relapse of Hairy cell leukemia, following a period of remission.
What is the importance of accurate coding for Hairy cell leukemia?
Accurate coding is essential for proper billing, treatment planning, and ensuring continuity of care. It also aids in public health reporting and research on the disease.
Clinical Notes
SOAP notes
DAP notes
AI medical notes