Overview of CPT Code 22142: Injection of therapeutic substance into joint or bursa
CPT Code 22142 refers to the injection of a therapeutic substance directly into a joint or bursa to alleviate pain, reduce inflammation, or improve joint function. This procedure is commonly used in the management of various musculoskeletal conditions.
When CPT Code 22142 is Used?
This code is applicable in several clinical scenarios, including but not limited to:
- Osteoarthritis of the knee or hip
- Rheumatoid arthritis flare-ups
- Bursitis in the shoulder or hip
- Tendinitis affecting the elbow or knee
- Joint effusions requiring therapeutic intervention
Symptoms Indicating This Procedure
Patients may report various symptoms that lead to the consideration of this injection, including:
- Persistent joint pain during movement or at rest
- Swelling or inflammation around the joint
- Stiffness or reduced range of motion
- Tenderness upon palpation of the joint
- Difficulty performing daily activities due to joint discomfort
Causes and Risk Factors
Several factors can contribute to the need for a therapeutic injection into a joint or bursa, including:
- Age-related degeneration of joint tissues
- Previous joint injuries or trauma
- Chronic inflammatory conditions like rheumatoid arthritis
- Obesity, which increases stress on weight-bearing joints
- Genetic predisposition to joint disorders
Diagnostic Tests Before Procedure
Prior to the injection, healthcare providers may utilize various diagnostic tests to confirm the need for the procedure, including:
- X-rays to assess joint structure and degeneration
- MRI scans for detailed imaging of soft tissues
- Ultrasound to visualize joint effusions
- Blood tests to rule out systemic inflammatory diseases
- Joint aspiration to analyze synovial fluid
Procedure Description
The injection procedure typically follows these steps:
- Patient is positioned comfortably, and the injection site is cleaned with antiseptic.
- Local anesthesia may be administered to minimize discomfort.
- Using a sterile syringe, the healthcare provider injects the therapeutic substance into the joint or bursa.
- The provider may use imaging guidance (ultrasound or fluoroscopy) to ensure accurate placement.
- Post-injection, the site is bandaged, and the patient is monitored briefly.
Preparation for the Procedure
Patients should follow these preparatory steps before the injection:
- Discuss any allergies to medications with the healthcare provider.
- Inform the provider of all current medications, especially blood thinners.
- Avoid taking anti-inflammatory medications for a few days prior to the procedure.
- Wear loose-fitting clothing to allow easy access to the injection site.
- Arrange for transportation if sedation is used during the procedure.
Recovery and Aftercare
Post-procedure, patients can expect the following:
- Rest the joint for 24-48 hours after the injection.
- Apply ice to the injection site to reduce swelling.
- Avoid strenuous activities for a few days.
- Follow any prescribed medication regimen for pain management.
- Schedule a follow-up appointment to assess the effectiveness of the injection.
Possible Complications
While generally safe, this procedure may carry some risks, including:
- Infection at the injection site
- Bleeding or bruising
- Allergic reaction to the injected substance
- Temporary increase in pain or swelling
- Nerve or tissue damage if not performed correctly


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Learn morePost-Procedure Follow-Up
Follow-up care is essential to monitor recovery and effectiveness:
- Typically scheduled 1-2 weeks after the injection.
- Assessment of pain relief and joint function improvement.
- Discussion of any side effects or complications experienced.
- Consideration of additional treatments if necessary.
Alternative Treatments
Patients may consider these non-surgical options:
- Physical therapy to strengthen surrounding muscles.
- Oral anti-inflammatory medications.
- Corticosteroid pills for systemic inflammation.
- Topical analgesics for localized pain relief.
- Acupuncture or chiropractic care for pain management.
Home Care Tips
To aid recovery, patients can follow these home care tips:
- Keep the injection site clean and dry.
- Monitor for signs of infection, such as increased redness or warmth.
- Engage in gentle range-of-motion exercises as tolerated.
- Stay hydrated and maintain a balanced diet to support healing.
- Use over-the-counter pain relievers as directed by the provider.
Patient Education & Prevention
To prevent recurrence of joint issues, consider these educational points:
- Maintain a healthy weight to reduce joint stress.
- Engage in regular low-impact exercise to strengthen joints.
- Incorporate flexibility and stretching exercises into routines.
- Avoid repetitive motions that strain the joints.
- Seek early treatment for joint pain to prevent worsening conditions.
Billing and Coding Information
CPT Code: 22142
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- RT - Right side
- LT - Left side
Average Cost and Insurance Coverage
The cost of this procedure can vary widely based on location and insurance:
- Average cost ranges from $200 to $1,500.
- Insurance may cover the procedure if deemed medically necessary.
- Patients should verify coverage with their insurance provider.
- Out-of-pocket costs may apply depending on the plan.
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