Overview of CPT Code 22122: Excision, tumor, soft tissue of neck or thorax, greater than 4 cm
CPT Code 22122 refers to the surgical excision of a tumor located in the soft tissue of the neck or thorax that measures greater than 4 cm. This procedure is typically performed to remove malignant or benign tumors that may cause discomfort, obstruct normal function, or pose a risk of malignancy.
When CPT Code 22122 is Used?
This code is applicable in various clinical scenarios, including:
- Presence of a large soft tissue tumor in the neck or thorax.
- Tumors that are symptomatic, causing pain or discomfort.
- Suspicion of malignancy based on imaging or physical examination.
- Need for definitive diagnosis through histopathological examination.
Symptoms Indicating This Procedure
Patients may report the following symptoms that could indicate the need for this procedure:
- A noticeable lump or mass in the neck or thorax.
- Pain or tenderness in the area of the tumor.
- Difficulty swallowing or breathing if the tumor is compressing nearby structures.
- Changes in voice or hoarseness due to tumor involvement.
Causes and Risk Factors
Several factors can contribute to the development of soft tissue tumors in the neck or thorax:
- Genetic predisposition to certain types of tumors.
- Previous radiation exposure to the neck or thorax.
- Chronic inflammation or irritation in the area.
- Certain hereditary syndromes that increase cancer risk.
Diagnostic Tests Before Procedure
Before proceeding with the excision, several diagnostic tests may be conducted:
- Ultrasound imaging to assess the size and characteristics of the tumor.
- CT or MRI scans for detailed visualization of the tumor and surrounding structures.
- Biopsy to determine the nature of the tumor (benign or malignant).
- Blood tests to evaluate overall health and any underlying conditions.
Procedure Description
The excision procedure typically follows these steps:
- Patient is positioned comfortably, and the area is cleaned and sterilized.
- Local anesthesia or sedation is administered to ensure patient comfort.
- An incision is made over the tumor to access the soft tissue.
- The tumor is carefully excised along with a margin of healthy tissue.
- The incision is closed with sutures, and a sterile dressing is applied.
Preparation for the Procedure
Patients should follow these steps to prepare for the excision:
- Consult with the surgeon about any medications being taken.
- Avoid blood thinners and certain supplements as advised.
- Arrange for transportation to and from the procedure.
- Follow fasting instructions if sedation is planned.
Recovery and Aftercare
Post-procedure recovery typically involves:
- Resting for the first few days after surgery.
- Keeping the surgical site clean and dry.
- Monitoring for signs of infection, such as increased redness or discharge.
- Taking prescribed pain medications as needed.
Possible Complications
While generally safe, this procedure carries some risks, including:
- Infection at the surgical site.
- Excessive bleeding during or after the procedure.
- Scarring or changes in skin sensation.
- Recurrence of the tumor if not completely excised.


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Learn morePost-Procedure Follow-Up
Follow-up care is essential for monitoring recovery:
- Schedule a follow-up appointment within 1-2 weeks post-surgery.
- Review pathology results to determine if further treatment is needed.
- Monitor healing and address any concerns regarding the surgical site.
Alternative Treatments
In some cases, alternative management options may include:
- Observation for small, asymptomatic tumors.
- Radiation therapy for non-surgical candidates.
- Chemotherapy for malignant tumors, depending on type and stage.
Home Care Tips
Patients can follow these tips for effective home care:
- Keep the incision site clean and dry.
- Avoid strenuous activities until cleared by the doctor.
- Use ice packs to reduce swelling if recommended.
- Follow dietary recommendations if sedation was used.
Patient Education & Prevention
To reduce the risk of recurrence, patients should consider:
- Regular check-ups to monitor for new growths.
- Healthy lifestyle choices, including diet and exercise.
- Awareness of any changes in the body and prompt reporting to a healthcare provider.
Billing and Coding Information
CPT Code: 22122
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- 59 - Distinct procedural service
Average Cost and Insurance Coverage
The cost for this procedure can vary widely:
- Average cost ranges from $2,000 to $5,000 depending on facility and complexity.
- Most insurance plans cover this procedure if deemed medically necessary.
Related CPT Codes
References and Sources