Overview of CPT Code 21742: Radiologic Guidance for Needle Biopsy
CPT Code 21742 refers to the use of radiologic guidance during a needle biopsy procedure, allowing for precise targeting of tissue samples from suspicious lesions or masses.
When CPT Code 21742 is Used?
This code is applicable in various clinical scenarios.
- Suspicious breast masses identified on mammography.
- Lung nodules detected via chest imaging.
- Liver lesions seen on ultrasound or CT scans.
- Lymph nodes with abnormal characteristics on imaging studies.
Symptoms Indicating This Procedure
Patients may present with various symptoms that warrant a needle biopsy.
- Palpable lumps or masses in the breast or other areas.
- Unexplained weight loss.
- Persistent cough or respiratory issues.
- Abnormal imaging findings without clear diagnosis.
Causes and Risk Factors
Several factors may increase the likelihood of needing a needle biopsy.
- Family history of breast or lung cancer.
- Previous cancer diagnoses.
- Age-related risk factors, particularly over 50.
- Exposure to carcinogens or radiation.
Diagnostic Tests Before Procedure
Prior to the biopsy, certain tests are typically performed.
- Mammography for breast lesions.
- CT scans for lung or abdominal masses.
- Ultrasound to guide needle placement.
- MRI for detailed imaging of soft tissues.
Procedure Description
The procedure involves several key steps.
- Patient is positioned appropriately based on the biopsy site.
- Skin is cleaned and numbed with local anesthesia.
- Imaging guidance (ultrasound, CT, or fluoroscopy) is used to locate the target area.
- A thin needle is inserted through the skin to obtain tissue samples.
- Multiple samples may be taken to ensure adequate tissue for diagnosis.
Preparation for the Procedure
Patients should follow specific guidelines before the biopsy.
- Avoid blood thinners or anti-inflammatory medications as directed.
- Inform the physician of any allergies, especially to anesthetics.
- Wear comfortable clothing and arrange for transportation if sedation is used.
- Follow any fasting instructions if applicable.
Recovery and Aftercare
Post-procedure care is essential for recovery.
- Rest for the remainder of the day after the procedure.
- Apply ice packs to the biopsy site to reduce swelling.
- Monitor for signs of infection, such as increased redness or discharge.
- Follow up with the physician for results and further instructions.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Bleeding at the biopsy site.
- Infection in the area of the biopsy.
- Pain or discomfort post-procedure.
- Pneumothorax if performed on lung tissue.


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Learn morePost-Procedure Follow-Up
Follow-up care is crucial for monitoring recovery.
- Schedule a follow-up appointment within a week to discuss results.
- Contact the physician if experiencing severe pain or unusual symptoms.
- Regular check-ups may be needed based on biopsy results.
Alternative Treatments
There are non-invasive options available.
- Watchful waiting for benign conditions.
- Imaging surveillance for small, non-suspicious lesions.
- Medication management for symptomatic relief.
Home Care Tips
Patients can take steps to aid recovery at home.
- Keep the biopsy site clean and dry.
- Avoid strenuous activities for a few days.
- Take prescribed pain medications as needed.
- Stay hydrated and maintain a balanced diet.
Patient Education & Prevention
Education is key to prevention and early detection.
- Regular screenings and imaging as recommended by healthcare providers.
- Awareness of personal and family medical history.
- Healthy lifestyle choices to reduce cancer risk.
Billing and Coding Information
CPT Code: 21742
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- LT - Left side
- RT - Right side
Average Cost and Insurance Coverage
Costs can vary based on location and insurance.
- Average cost ranges from $1,000 to $3,000.
- Most insurance plans cover the procedure if deemed medically necessary.
- Out-of-pocket costs depend on the patient's insurance plan.
Related CPT Codes
References and Sources