Overview of CPT Code 21603: Excision, tumor, soft tissue of neck or thorax, subcutaneous; excised diameter over 4 cm
CPT Code 21603 refers to the surgical excision of a tumor located in the soft tissue of the neck or thorax, specifically when the excised diameter exceeds 4 cm. This procedure is typically performed to remove tumors that may be benign or malignant, and it is crucial for both diagnostic and therapeutic purposes.
When CPT Code 21603 is Used?
This code is applicable in various clinical scenarios, including:
- Presence of a large soft tissue tumor in the neck or thorax.
- Suspicion of malignancy based on imaging or physical examination.
- Tumors causing symptoms such as pain or discomfort.
- Need for definitive diagnosis through histopathological examination.
Symptoms Indicating This Procedure
Patients may report the following symptoms that could necessitate this procedure:
- A noticeable lump or mass in the neck or thorax.
- Pain or tenderness in the area of the tumor.
- Difficulty swallowing or breathing if the tumor is compressing nearby structures.
- Changes in skin appearance over the tumor, such as discoloration or ulceration.
Causes and Risk Factors
Several factors may contribute to the development of soft tissue tumors in the neck or thorax:
- Genetic predisposition to certain types of tumors.
- Previous radiation exposure to the neck or thorax.
- Chronic inflammation or irritation in the area.
- Age, as certain tumors are more common in older adults.
Diagnostic Tests Before Procedure
Before proceeding with the excision, the following diagnostic tests may be conducted:
- Ultrasound imaging to assess the size and characteristics of the tumor.
- CT or MRI scans for detailed visualization of the tumor and surrounding structures.
- Biopsy to determine the nature of the tumor (benign or malignant).
- Blood tests to evaluate overall health and any underlying conditions.
Procedure Description
The excision procedure typically follows these steps:
- Patient is positioned comfortably, and the area is cleaned and sterilized.
- Local anesthesia is administered to numb the area, or general anesthesia may be used.
- An incision is made over the tumor to access the soft tissue.
- The tumor is carefully excised along with a margin of healthy tissue.
- The incision is closed with sutures, and a sterile dressing is applied.
Preparation for the Procedure
Patients should follow these steps to prepare for the excision:
- Consult with the surgeon about any medications being taken.
- Avoid blood thinners and certain supplements as advised by the physician.
- Arrange for transportation to and from the procedure.
- Follow fasting instructions if general anesthesia is planned.
Recovery and Aftercare
Post-procedure recovery typically involves:
- Resting for the first 24 hours after the procedure.
- Keeping the surgical site clean and dry.
- Monitoring for signs of infection, such as increased redness or discharge.
- Taking prescribed pain medications as needed.
Possible Complications
While generally safe, this procedure carries some risks, including:
- Infection at the surgical site.
- Excessive bleeding during or after the procedure.
- Scarring or changes in skin sensation.
- Recurrence of the tumor if not completely excised.


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Learn morePost-Procedure Follow-Up
Follow-up care is essential for monitoring recovery:
- A follow-up appointment is typically scheduled within 1-2 weeks post-surgery.
- Sutures may be removed during this visit if applicable.
- Pathology results will be discussed to determine further treatment if necessary.
- Regular check-ups may be recommended to monitor for recurrence.
Alternative Treatments
In some cases, alternative management options may include:
- Observation for small, asymptomatic tumors.
- Radiation therapy for non-surgical candidates or specific tumor types.
- Chemotherapy for malignant tumors, depending on the diagnosis.
Home Care Tips
Patients can follow these tips for effective home care:
- Keep the surgical area clean and dry.
- Avoid strenuous activities for at least a week.
- Follow dietary recommendations if nausea or discomfort occurs.
- Stay hydrated and maintain a balanced diet to support healing.
Patient Education & Prevention
To reduce the risk of recurrence, patients should consider:
- Regular skin checks for new or changing lesions.
- Avoiding known risk factors, such as excessive sun exposure.
- Maintaining a healthy lifestyle to support overall well-being.
- Following up with healthcare providers for any concerning symptoms.
Billing and Coding Information
CPT Code: 21603
Category: Surgical Procedures
Common Modifiers:
Average Cost and Insurance Coverage
The cost for this procedure can vary widely:
- Average costs range from $2,000 to $5,000 depending on facility and complexity.
- Most insurance plans cover this procedure if deemed medically necessary.
- Patients should verify coverage details with their insurance provider.
Related CPT Codes
- 21600 - Excision of benign skin lesion, face, ears, scalp, neck, hands, feet, and genitalia.
- 21601 - Excision of benign skin lesion, face, ears, scalp, neck, hands, feet, and genitalia; excised diameter over 4.0 cm.
- 21550 - Excision, tumor, soft tissue of neck or thorax
- 21552 - Excision, tumor, soft tissue of neck or thorax
References and Sources