Overview of CPT Code 21485: Removal of Tumor, Soft Tissue, Neck
CPT Code 21485 refers to the surgical procedure for the removal of a tumor located in the soft tissue of the neck. This procedure is typically performed to excise benign or malignant tumors that may be causing discomfort, obstructing airways, or posing a risk of malignancy.
When CPT Code 21485 is Used?
This code is applicable in various clinical scenarios, including but not limited to:
- Presence of a palpable tumor in the neck region.
- Suspicion of malignancy based on imaging or biopsy results.
- Tumors causing symptoms such as pain, swelling, or difficulty swallowing.
- Follow-up treatment for previously diagnosed tumors.
Symptoms Indicating This Procedure
Patients may report several symptoms that lead to the consideration of this procedure, including:
- A noticeable lump or mass in the neck.
- Pain or discomfort in the neck area.
- Difficulty swallowing or breathing.
- Changes in voice or hoarseness.
- Swelling or inflammation around the tumor site.
Causes and Risk Factors
Various factors can contribute to the development of tumors in the soft tissue of the neck, including:
- Genetic predisposition to certain types of tumors.
- Previous history of cancer.
- Exposure to radiation or carcinogenic substances.
- Chronic inflammation or infection in the neck region.
Diagnostic Tests Before Procedure
Prior to the procedure, several diagnostic tests may be conducted to assess the tumor's characteristics:
- Ultrasound imaging to evaluate the size and structure of the tumor.
- CT or MRI scans for detailed imaging of the neck.
- Biopsy to determine the nature of the tumor (benign or malignant).
- Blood tests to assess overall health and detect any underlying conditions.
Procedure Description
The removal of a soft tissue tumor in the neck typically follows these steps:
- Patient is positioned comfortably, and anesthesia is administered.
- An incision is made over the tumor site to access the tissue.
- The tumor is carefully excised along with a margin of healthy tissue.
- The incision is closed with sutures or staples.
- Dressing is applied to the surgical site.
Preparation for the Procedure
Patients should follow these guidelines to prepare for the surgery:
- Consult with the surgeon about medications to avoid prior to surgery.
- Arrange for transportation to and from the procedure.
- Avoid eating or drinking for a specified period before the surgery.
- Discuss any allergies or medical conditions with the healthcare provider.
Recovery and Aftercare
Post-operative recovery typically involves the following:
- Resting for a few days after the procedure.
- Keeping the surgical site clean and dry.
- Taking prescribed pain medications as needed.
- Monitoring for signs of infection, such as increased redness or discharge.
Possible Complications
While generally safe, this procedure carries some risks, including:
- Infection at the surgical site.
- Bleeding or hematoma formation.
- Nerve damage leading to numbness or weakness.
- Scarring or cosmetic concerns.


Secure, compliant, and built for trust
HIPAA-compliant and designed with privacy in mind, your patient’s data is protected. Focus on care while we safeguard your information.
Learn morePost-Procedure Follow-Up
Follow-up appointments are crucial for monitoring recovery:
- Initial follow-up within one week to assess healing.
- Further visits as needed based on pathology results.
- Regular check-ups to monitor for any signs of recurrence.
Alternative Treatments
In some cases, non-surgical options may be considered, such as:
- Observation for benign tumors without symptoms.
- Radiation therapy for certain types of malignant tumors.
- Chemotherapy for systemic treatment of cancer.
Home Care Tips
Patients can follow these tips for effective home care:
- Keep the surgical area clean and dry.
- Avoid strenuous activities for a few weeks.
- Follow dietary recommendations if swallowing is affected.
- Stay hydrated and maintain a balanced diet for healing.
Patient Education & Prevention
To reduce the risk of recurrence, patients should consider:
- Regular check-ups with healthcare providers.
- Awareness of any new symptoms in the neck area.
- Healthy lifestyle choices, including diet and exercise.
- Avoiding known carcinogens and maintaining a healthy environment.
Billing and Coding Information
CPT Code: 21485
Category: Surgical Procedures
Common Modifiers:
- 50 (Bilateral procedure)
- RT (Right side)
- LT (Left side)
Average Cost and Insurance Coverage
The cost of this procedure can vary widely based on several factors:
- Average cost ranges from $2,000 to $5,000.
- Insurance may cover the procedure if deemed medically necessary.
- Out-of-pocket costs depend on the patient's insurance plan.
Related CPT Codes
References and Sources