Overview of CPT Code 21335: Excision of benign skin lesion, face, ears, scalp, neck
CPT Code 21335 refers to the surgical excision of benign skin lesions located on the face, ears, scalp, or neck. This procedure is performed to remove non-cancerous growths that may cause cosmetic concerns or discomfort.
When CPT Code 21335 is Used?
This procedure is indicated in various clinical scenarios.
- Presence of a benign skin lesion causing cosmetic concerns.
- Lesions that are symptomatic, such as itching or irritation.
- Lesions that have changed in appearance or size.
- Patient request for removal of a lesion for aesthetic reasons.
Symptoms Indicating This Procedure
Patients may report several symptoms that lead to the consideration of this procedure.
- Visible skin growths on the face, ears, scalp, or neck.
- Itching or irritation at the site of the lesion.
- Bleeding or oozing from the lesion.
- Changes in color, size, or shape of the lesion.
Causes and Risk Factors
Understanding the causes and risk factors can help in prevention.
- Genetic predisposition to skin lesions.
- Sun exposure leading to skin changes.
- Previous skin injuries or infections.
- Certain skin conditions like seborrheic keratosis.
Diagnostic Tests Before Procedure
Before the excision, certain diagnostic tests may be performed.
- Physical examination of the lesion.
- Dermatoscopy to assess the lesion's characteristics.
- Biopsy if there is suspicion of malignancy.
Procedure Description
The excision procedure involves several key steps.
- Patient is positioned comfortably and the area is cleaned.
- Local anesthesia is administered to numb the area.
- The surgeon excises the lesion along with a margin of healthy tissue.
- The wound is closed with sutures or adhesive strips.
- Post-operative care instructions are provided.
Preparation for the Procedure
Patients should follow these steps to prepare for the excision.
- Avoid blood thinners like aspirin or ibuprofen a week prior.
- Discuss any allergies with the healthcare provider.
- Arrive with clean skin, free of makeup or lotions.
- Have a responsible adult accompany you for post-procedure care.
Recovery and Aftercare
Post-procedure recovery is crucial for healing.
- Keep the area clean and dry for the first few days.
- Change dressings as instructed by the healthcare provider.
- Avoid strenuous activities for at least a week.
- Monitor for signs of infection such as increased redness or pus.
Possible Complications
While generally safe, there are potential risks involved.
- Infection at the site of excision.
- Scarring or changes in skin texture.
- Bleeding or hematoma formation.
- Allergic reaction to anesthesia.


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Learn morePost-Procedure Follow-Up
Follow-up is essential to ensure proper healing.
- Schedule a follow-up appointment within 1-2 weeks.
- Sutures may need to be removed after 7-14 days.
- Monitor the site for any unusual changes.
Alternative Treatments
There are non-surgical options for managing benign lesions.
- Cryotherapy to freeze off the lesion.
- Topical treatments for certain skin conditions.
- Laser therapy for cosmetic concerns.
Home Care Tips
Patients can follow these tips for better recovery.
- Keep the excision site clean and dry.
- Avoid picking at scabs or lesions.
- Use over-the-counter pain relief as needed.
- Stay hydrated and maintain a balanced diet.
Patient Education & Prevention
Educating patients can help prevent future lesions.
- Use sunscreen to protect skin from UV damage.
- Regular skin checks for new or changing lesions.
- Avoid excessive sun exposure, especially during peak hours.
- Consult a dermatologist for any skin concerns.
Billing and Coding Information
CPT Code: 21335
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- 59 - Distinct procedural service
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $200 to $1,500.
- Insurance may cover the procedure if deemed medically necessary.
- Out-of-pocket costs depend on the insurance plan.
Related CPT Codes
- 11400 - Excision, benign skin lesion, face, ears, scalp, neck; excised diameter over 4.0 cm.
- 11401 - Excision, benign skin lesion, face, ears, scalp, neck; excised diameter over 4.0 cm.
- 11402 - Excision, benign skin lesion, face, ears, scalp, neck; excised diameter over 4.0 cm.
- 11406 - Excision, benign skin lesion; face, ears, scalp, neck, excised diameter over 4.0 cm
- 11403 - Excision, benign skin lesion, face, ears, scalp; excised diameter over 4.0 cm.
References and Sources