Overview of CPT Code 21325: Excision of benign lesion, face, ears, scalp, neck
CPT Code 21325 refers to the surgical excision of a benign lesion located on the face, ears, scalp, or neck. This procedure is typically performed to remove non-cancerous growths that may cause cosmetic concerns or discomfort.
When CPT Code 21325 is Used?
This code is applicable in various clinical scenarios.
- Presence of a benign tumor or cyst causing discomfort or cosmetic issues.
- Lesions that are growing or changing in appearance.
- Skin tags or moles that are bothersome to the patient.
- Lesions that require histological examination to rule out malignancy.
Symptoms Indicating This Procedure
Patients may report several symptoms that lead to the consideration of this procedure.
- Visible growths on the skin that are changing in size or color.
- Pain or tenderness in the area of the lesion.
- Itching or irritation associated with the lesion.
- Bleeding or oozing from the lesion.
Causes and Risk Factors
Understanding the causes and risk factors can help in prevention.
- Genetic predisposition to skin growths.
- Sun exposure leading to skin changes.
- Previous skin injuries or infections.
- Certain skin conditions like seborrheic keratosis.
Diagnostic Tests Before Procedure
Several diagnostic tests may be performed prior to the excision.
- Physical examination of the lesion.
- Dermatoscopy to assess the characteristics of the lesion.
- Biopsy if malignancy is suspected.
Procedure Description
The excision procedure follows a systematic approach.
- Patient is positioned comfortably and the area is cleaned.
- Local anesthesia is administered to numb the area.
- The surgeon makes an incision around the lesion.
- The lesion is carefully excised along with a margin of healthy tissue.
- The incision is closed with sutures or adhesive strips.
Preparation for the Procedure
Proper preparation is essential for a smooth procedure.
- Avoid blood thinners and certain medications as advised by the physician.
- Inform the doctor about any allergies or medical conditions.
- Arrive at the facility with a clean face and neck area.
Recovery and Aftercare
Post-procedure care is crucial for healing.
- Keep the area clean and dry for the first few days.
- Apply prescribed ointments to promote healing.
- Avoid sun exposure on the excised area.
- Follow up for suture removal as directed.
Possible Complications
While complications are rare, they can occur.
- Infection at the site of excision.
- Scarring or changes in skin pigmentation.
- Recurrence of the lesion.
- Allergic reaction to anesthesia.


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Learn morePost-Procedure Follow-Up
Follow-up is important to monitor healing.
- Schedule a follow-up appointment within 1-2 weeks.
- Monitor for signs of infection or complications.
- Discuss pathology results if a biopsy was performed.
Alternative Treatments
There are non-surgical options available.
- Cryotherapy to freeze off benign lesions.
- Laser therapy for superficial lesions.
- Topical treatments for certain skin conditions.
Home Care Tips
Simple home care can aid recovery.
- Keep the excision site clean and dry.
- Avoid picking at scabs or sutures.
- Use sunscreen to protect the area from UV rays.
Patient Education & Prevention
Education is key to preventing recurrence.
- Regular skin checks for new or changing lesions.
- Use sunscreen to protect against sun damage.
- Avoid excessive sun exposure, especially during peak hours.
Billing and Coding Information
CPT Code: 21325
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- 59 - Distinct procedural service
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $200 to $1,500 depending on complexity.
- Most insurance plans cover the procedure if deemed medically necessary.
Related CPT Codes
- 21320 - Excision of benign skin lesion, face, ears, scalp, neck
- 11400 - Excision, benign skin lesion, face, ears, scalp, neck; excised diameter over 4.0 cm.
- 11401 - Excision, benign skin lesion, face, ears, scalp, neck; excised diameter over 4.0 cm.
- 11402 - Excision, benign skin lesion, face, ears, scalp, neck; excised diameter over 4.0 cm.
References and Sources