Overview of CPT Code 21263: Injection of implantable drug delivery device, craniofacial region
CPT Code 21263 refers to the procedure involving the injection of an implantable drug delivery device in the craniofacial region. This device is designed to provide localized medication delivery for conditions affecting the head and face.
When CPT Code 21263 is Used?
This procedure is indicated in specific clinical scenarios.
- Chronic pain management in craniofacial conditions.
- Treatment of localized infections requiring sustained medication.
- Management of tumors in the craniofacial region.
- Conditions requiring long-term medication delivery without frequent injections.
Symptoms Indicating This Procedure
Patients may present with various symptoms that warrant this procedure.
- Persistent pain in the craniofacial area.
- Swelling or inflammation in the face.
- Recurrent infections in the craniofacial region.
- Difficulty in managing symptoms with oral medications.
Causes and Risk Factors
Several factors can lead to the need for this procedure.
- Chronic inflammatory conditions.
- Previous surgeries in the craniofacial area.
- Tumors or growths in the craniofacial region.
- Infections that are difficult to treat with standard medications.
Diagnostic Tests Before Procedure
Certain tests may be required to guide the procedure.
- Imaging studies such as CT or MRI to assess the craniofacial structure.
- Blood tests to evaluate infection or inflammation.
- Biopsy of any suspicious lesions if indicated.
Procedure Description
The procedure involves several key steps.
- Patient is positioned comfortably and the area is cleaned.
- Local anesthesia is administered to minimize discomfort.
- A small incision may be made to access the craniofacial region.
- The implantable drug delivery device is inserted carefully.
- The incision is closed with sutures or adhesive, and a dressing is applied.
Preparation for the Procedure
Patients should follow specific guidelines before the procedure.
- Discuss any medications with the healthcare provider.
- Avoid blood thinners or anti-inflammatory medications as advised.
- Arrive at the facility with a responsible adult for post-procedure assistance.
- Follow fasting instructions if sedation is planned.
Recovery and Aftercare
Post-procedure care is crucial for recovery.
- Rest for the first 24 hours post-procedure.
- Keep the incision site clean and dry.
- Follow up with prescribed medications for pain management.
- Attend follow-up appointments to monitor healing.
Possible Complications
As with any procedure, there are potential risks.
- Infection at the injection site.
- Allergic reaction to the implant or medication.
- Nerve damage leading to numbness or weakness.
- Device malfunction or displacement.


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Learn morePost-Procedure Follow-Up
Regular follow-up is essential for monitoring.
- Initial follow-up within one week to assess healing.
- Subsequent visits as needed based on symptoms.
- Long-term monitoring for device function and medication efficacy.
Alternative Treatments
There are non-surgical options available.
- Oral medications for pain management.
- Physical therapy for craniofacial conditions.
- Injections of corticosteroids or other medications.
- Acupuncture or alternative therapies for symptom relief.
Home Care Tips
Patients can take steps to aid recovery at home.
- Apply ice packs to reduce swelling.
- Avoid strenuous activities for a few days.
- Monitor the incision site for signs of infection.
- Stay hydrated and maintain a balanced diet.
Patient Education & Prevention
Education is key to preventing complications.
- Understand the signs of infection and when to seek help.
- Discuss lifestyle changes that may reduce symptoms.
- Adhere to follow-up schedules for monitoring.
- Educate on the importance of medication adherence.
Billing and Coding Information
CPT Code: 21263
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- LT - Left side
- RT - Right side
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $2,000 to $5,000.
- Insurance may cover the procedure if deemed medically necessary.
- Check with your insurance provider for specific coverage details.
Related CPT Codes
References and Sources