Overview of CPT Code 21248: Injection of implantable drug delivery system, craniofacial
CPT Code 21248 refers to the injection of an implantable drug delivery system specifically designed for craniofacial applications. This procedure is utilized to manage chronic pain or deliver medication directly to targeted areas in the craniofacial region.
When CPT Code 21248 is Used?
This procedure is indicated in various clinical scenarios.
- Management of chronic pain in craniofacial regions.
- Delivery of localized medication for conditions like trigeminal neuralgia.
- Treatment of specific craniofacial tumors requiring targeted therapy.
Symptoms Indicating This Procedure
Patients may present with several symptoms that warrant this procedure.
- Severe facial pain or discomfort.
- Persistent headaches localized to the craniofacial area.
- Neuropathic pain symptoms such as tingling or burning sensations.
Causes and Risk Factors
Understanding the underlying causes and risk factors is crucial.
- Chronic conditions such as migraines or cluster headaches.
- Previous facial trauma or surgery.
- Genetic predisposition to craniofacial pain syndromes.
Diagnostic Tests Before Procedure
Several diagnostic tests may be performed to guide the procedure.
- MRI or CT scans to assess craniofacial structures.
- Nerve conduction studies to evaluate nerve function.
- Pain assessments and questionnaires to determine pain levels.
Procedure Description
The procedure involves several key steps.
- Patient is positioned comfortably and local anesthesia is administered.
- The site for the injection is cleaned and sterilized.
- The implantable drug delivery system is inserted into the designated craniofacial area.
- The system is secured and the incision is closed with sutures or adhesive.
Preparation for the Procedure
Patients should follow specific guidelines before the procedure.
- Avoid blood thinners and anti-inflammatory medications for a week prior.
- Discuss any allergies with the healthcare provider.
- Arrange for transportation post-procedure due to sedation.
Recovery and Aftercare
Post-procedure care is essential for optimal recovery.
- Rest for at least 24 hours following the procedure.
- Keep the injection site clean and dry.
- Follow up with prescribed pain management medications as needed.
Possible Complications
Like any medical procedure, there are potential risks involved.
- Infection at the injection site.
- Nerve damage leading to altered sensation.
- Allergic reactions to the implant or medication.


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Learn morePost-Procedure Follow-Up
Regular follow-up is important for monitoring recovery.
- Initial follow-up within one week to assess healing.
- Subsequent visits every month for the first three months.
- Long-term follow-up every six months to evaluate the effectiveness of the implant.
Alternative Treatments
There are several non-surgical options available.
- Physical therapy to manage pain and improve function.
- Medication management including oral pain relievers.
- Nerve blocks or other minimally invasive procedures.
Home Care Tips
Patients can take steps at home to aid recovery.
- Apply ice packs to the injection site to reduce swelling.
- Maintain a balanced diet to support healing.
- Engage in light activities as tolerated, avoiding strenuous exercise.
Patient Education & Prevention
Education is key to preventing recurrence.
- Understand triggers for craniofacial pain and avoid them.
- Maintain regular follow-ups with healthcare providers.
- Stay informed about new treatment options and pain management strategies.
Billing and Coding Information
CPT Code: 21248
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- LT - Left side
- RT - Right side
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $5,000 to $15,000.
- Insurance may cover a portion depending on medical necessity.
- Patients should verify coverage with their insurance provider.
Related CPT Codes
References and Sources