Overview of CPT Code 21208: Injection of bone cement into vertebral body
CPT Code 21208 refers to the procedure of injecting bone cement into a vertebral body, primarily used to treat vertebral compression fractures. This minimally invasive technique aims to stabilize the spine and alleviate pain.
When CPT Code 21208 is Used?
This procedure is indicated in specific clinical scenarios.
- Vertebral compression fractures due to osteoporosis.
- Pathological fractures from tumors or malignancies.
- Severe back pain associated with vertebral fractures not responding to conservative treatment.
Symptoms Indicating This Procedure
Patients may present with various symptoms that warrant this procedure.
- Severe localized back pain.
- Pain that worsens with movement or standing.
- Numbness or weakness in the legs.
- Difficulty walking or performing daily activities.
Causes and Risk Factors
Understanding the underlying causes and risk factors is crucial for prevention.
- Osteoporosis leading to weakened bones.
- Age-related bone density loss.
- Previous history of fractures.
- Certain cancers that affect bone integrity.
Diagnostic Tests Before Procedure
Several diagnostic tests help confirm the need for this procedure.
- X-rays to visualize fractures.
- MRI to assess the extent of injury and surrounding tissues.
- CT scans for detailed imaging of the vertebrae.
Procedure Description
The procedure involves several key steps.
- Patient is positioned comfortably, often lying on their stomach.
- Local anesthesia is administered to numb the area.
- A small incision is made to insert a needle into the vertebral body.
- Bone cement is mixed and injected into the vertebra to stabilize it.
- The needle is removed, and the incision is closed.
Preparation for the Procedure
Proper preparation is essential for a successful outcome.
- Discuss any medications with your doctor, especially blood thinners.
- Arrange for someone to drive you home post-procedure.
- Follow any fasting instructions provided by your healthcare team.
Recovery and Aftercare
Post-procedure care is vital for recovery.
- Rest for the first 24 hours after the procedure.
- Gradually resume normal activities as tolerated.
- Follow up with your doctor for pain management and monitoring.
Possible Complications
While generally safe, there are potential risks involved.
- Infection at the injection site.
- Allergic reaction to the bone cement.
- Nerve damage or increased pain.
- Leakage of cement into surrounding tissues.


Secure, compliant, and built for trust
HIPAA-compliant and designed with privacy in mind, your patient’s data is protected. Focus on care while we safeguard your information.
Learn morePost-Procedure Follow-Up
Regular follow-up is important for monitoring recovery.
- Initial follow-up within one week to assess pain and mobility.
- Subsequent visits as needed based on recovery progress.
- Imaging studies may be repeated to evaluate the success of the procedure.
Alternative Treatments
There are several non-surgical options available.
- Physical therapy to strengthen back muscles.
- Pain management with medications.
- Bracing to support the spine.
- Vertebroplasty or kyphoplasty as alternative surgical options.
Home Care Tips
Simple home care can aid in recovery.
- Apply ice packs to reduce swelling and pain.
- Avoid heavy lifting or strenuous activities.
- Maintain a healthy diet to support bone health.
Patient Education & Prevention
Education is key to preventing future issues.
- Engage in weight-bearing exercises to strengthen bones.
- Ensure adequate intake of calcium and vitamin D.
- Regular screenings for osteoporosis, especially in at-risk populations.
Billing and Coding Information
CPT Code: 21208
Category: Surgical Procedures
Common Modifiers:
- -50 Bilateral procedure
- -59 Distinct procedural service
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $5,000 to $15,000.
- Most insurance plans cover the procedure if deemed medically necessary.
- Out-of-pocket costs depend on individual insurance plans.
References and Sources