Overview of CPT Code 21206: Injection of bone marrow aspirate
CPT Code 21206 refers to the injection of bone marrow aspirate, a procedure where bone marrow is extracted and injected into a specific site to promote healing and regeneration of tissues.
When CPT Code 21206 is Used?
This procedure is indicated in various clinical scenarios.
- Treatment of osteonecrosis or avascular necrosis of the bone.
- Management of chronic non-healing wounds.
- Support in the healing of bone fractures.
- Enhancement of tissue regeneration in orthopedic surgeries.
Symptoms Indicating This Procedure
Patients may report several symptoms that lead to the consideration of this procedure.
- Persistent pain in the affected bone or joint.
- Swelling and inflammation around the injury site.
- Limited range of motion in the affected area.
- Signs of infection or delayed healing in chronic wounds.
Causes and Risk Factors
Several factors can contribute to the need for this procedure.
- Previous trauma or injury to the bone.
- Underlying conditions such as diabetes or vascular disease.
- History of smoking or excessive alcohol consumption.
- Genetic predisposition to bone disorders.
Diagnostic Tests Before Procedure
Certain tests are typically performed to guide the decision for this procedure.
- X-rays to assess bone structure and integrity.
- MRI scans to evaluate soft tissue and bone marrow conditions.
- Blood tests to check for infection or other underlying issues.
- Bone scans to identify areas of increased activity or damage.
Procedure Description
The procedure involves several key steps to ensure safety and effectiveness.
- Patient is positioned comfortably and the area is cleaned and sterilized.
- Local anesthesia is administered to minimize discomfort.
- A needle is inserted into the bone to aspirate bone marrow.
- The aspirated bone marrow is prepared for injection.
- The prepared bone marrow is injected into the targeted area.
Preparation for the Procedure
Patients should follow specific guidelines to prepare for the procedure.
- Discuss any medications with your healthcare provider, especially blood thinners.
- Avoid eating or drinking for a specified period before the procedure.
- Arrange for transportation home post-procedure if sedation is used.
- Wear comfortable clothing and avoid applying lotions or creams to the area.
Recovery and Aftercare
Post-procedure care is essential for optimal recovery.
- Rest the affected area and avoid strenuous activities for a few days.
- Apply ice to reduce swelling and discomfort.
- Follow up with your healthcare provider as instructed.
- Take prescribed medications for pain management as needed.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Infection at the injection site.
- Bleeding or hematoma formation.
- Nerve damage or injury to surrounding tissues.
- Allergic reaction to anesthesia or other materials used.


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Learn morePost-Procedure Follow-Up
Monitoring after the procedure is crucial for assessing recovery.
- Schedule a follow-up appointment within 1-2 weeks post-procedure.
- Report any unusual symptoms such as increased pain or swelling.
- Discuss the effectiveness of the treatment and any further steps needed.
Alternative Treatments
There are non-surgical options available for managing similar conditions.
- Physical therapy to improve mobility and strength.
- Medications such as anti-inflammatories or pain relievers.
- Corticosteroid injections to reduce inflammation.
- Use of orthotics or braces to support the affected area.
Home Care Tips
Patients can take simple steps at home to aid recovery.
- Keep the injection site clean and dry.
- Monitor for signs of infection such as redness or discharge.
- Stay hydrated and maintain a balanced diet to support healing.
- Engage in gentle exercises as recommended by your healthcare provider.
Patient Education & Prevention
Understanding how to prevent future issues is vital.
- Maintain a healthy lifestyle with regular exercise and a balanced diet.
- Avoid smoking and limit alcohol consumption.
- Manage chronic conditions effectively to reduce risks.
- Stay informed about bone health and seek regular check-ups.
Billing and Coding Information
CPT Code: 21206
Category: Surgical Procedures
Common Modifiers:
Average Cost and Insurance Coverage
Costs can vary based on location and insurance.
- Average cost ranges from $1,500 to $3,000.
- Most insurance plans cover the procedure if deemed medically necessary.
- Check with your insurance provider for specific coverage details.
Related CPT Codes
References and Sources