Overview of CPT Code 21204: Injection of implantable drug delivery device
CPT Code 21204 refers to the injection of an implantable drug delivery device, which is used to administer medication directly into a specific area of the body over an extended period. This procedure is commonly utilized in pain management and treatment of chronic conditions.
When CPT Code 21204 is Used?
This procedure is indicated in various clinical scenarios.
- Management of chronic pain conditions such as cancer pain.
- Treatment of severe spasticity in conditions like multiple sclerosis.
- Delivery of localized chemotherapy for certain tumors.
- Administration of hormones or other medications for specific endocrine disorders.
Symptoms Indicating This Procedure
Patients may present with various symptoms that warrant this procedure.
- Persistent pain that is unresponsive to oral medications.
- Severe muscle spasms or spasticity.
- Symptoms of localized disease requiring targeted therapy.
- Need for long-term medication management without frequent injections.
Causes and Risk Factors
Several factors may lead to the need for an implantable drug delivery device.
- Chronic pain syndromes.
- Neurological disorders such as multiple sclerosis.
- Certain types of cancer requiring localized treatment.
- Previous unsuccessful treatments with oral or injectable medications.
Diagnostic Tests Before Procedure
Prior to the procedure, certain diagnostic tests may be performed.
- Imaging studies such as MRI or CT scans to assess the area of treatment.
- Blood tests to evaluate overall health and medication levels.
- Nerve conduction studies if neurological involvement is suspected.
Procedure Description
The procedure involves several key steps.
- Patient is positioned comfortably and the area is cleaned and sterilized.
- Local anesthesia is administered to minimize discomfort.
- A small incision is made to place the drug delivery device.
- The device is implanted and secured in place.
- The incision is closed with sutures or adhesive strips.
Preparation for the Procedure
Patients should follow specific guidelines before the procedure.
- Discuss all medications with the healthcare provider, including over-the-counter drugs.
- Avoid blood thinners and certain supplements as advised.
- Arrive at the facility with a responsible adult for post-procedure transportation.
- Follow any fasting instructions if sedation is planned.
Recovery and Aftercare
Post-procedure recovery involves several considerations.
- Rest for the first 24 hours after the procedure.
- Keep the incision site clean and dry; follow wound care instructions.
- Monitor for signs of infection such as increased redness or discharge.
- Follow up with the healthcare provider for device checks and medication adjustments.
Possible Complications
As with any medical procedure, there are potential risks.
- Infection at the implantation site.
- Device malfunction or displacement.
- Nerve damage or persistent pain.
- Allergic reactions to the medication or device materials.


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Learn morePost-Procedure Follow-Up
Regular follow-up is essential for monitoring.
- Initial follow-up within one week to assess healing.
- Regular check-ups every few months to evaluate device function.
- Adjustments to medication dosages as needed based on patient response.
Alternative Treatments
There are several non-surgical options available.
- Oral medications for pain management.
- Physical therapy to improve mobility and reduce pain.
- Nerve blocks or epidural steroid injections.
- Transcutaneous electrical nerve stimulation (TENS) therapy.
Home Care Tips
Patients can take steps to aid recovery at home.
- Keep the incision site clean and dry.
- Avoid strenuous activities for at least a week.
- Take prescribed medications as directed.
- Use ice packs to reduce swelling if recommended.
Patient Education & Prevention
Education is key to preventing complications.
- Understand the signs of infection and when to seek help.
- Maintain a healthy lifestyle to support overall health.
- Adhere to follow-up appointments for device monitoring.
- Discuss any new symptoms with the healthcare provider promptly.
Billing and Coding Information
CPT Code: 21204
Category: Surgery
Common Modifiers:
- 50 - Bilateral procedure
- LT - Left side
- RT - Right side
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $5,000 to $15,000 depending on the device and facility.
- Most insurance plans cover the procedure if deemed medically necessary.
- Patients should verify coverage details with their insurance provider.
Related CPT Codes
References and Sources