Overview of CPT Code 21198: Injection of implantable drug delivery system
CPT Code 21198 refers to the injection of an implantable drug delivery system, which is a medical procedure used to administer medication directly into a specific area of the body over an extended period. This method is often utilized for chronic pain management, cancer treatment, or other conditions requiring consistent medication delivery.
When CPT Code 21198 is Used?
This procedure is indicated in various clinical scenarios, including but not limited to:
- Chronic pain management in patients who have not responded to oral medications.
- Cancer patients requiring localized chemotherapy.
- Patients with severe spasticity or muscle disorders.
- Management of certain neurological conditions.
Symptoms Indicating This Procedure
Patients may present with the following symptoms that indicate the need for this procedure:
- Persistent pain that interferes with daily activities.
- Severe muscle spasms or spasticity.
- Uncontrolled symptoms from cancer or other chronic conditions.
- Inadequate relief from traditional medication routes.
Causes and Risk Factors
Several factors may lead to the need for an implantable drug delivery system, including:
- Chronic pain conditions such as fibromyalgia or arthritis.
- Cancer diagnoses requiring ongoing treatment.
- Neurological disorders like multiple sclerosis.
- Previous unsuccessful treatments with oral medications.
Diagnostic Tests Before Procedure
Before the procedure, several diagnostic tests may be performed to ensure appropriateness:
- Imaging studies such as MRI or CT scans to assess the area of treatment.
- Blood tests to evaluate overall health and organ function.
- Pain assessments to determine the severity and location of symptoms.
Procedure Description
The procedure involves several key steps:
- Patient is positioned comfortably and the area of injection is cleaned.
- Local anesthesia is administered to minimize discomfort.
- A small incision is made to insert the drug delivery system.
- The system is placed in the appropriate location and secured.
- The incision is closed and dressed appropriately.
Preparation for the Procedure
Patients should follow these steps to prepare for the procedure:
- Discuss any medications with the healthcare provider, especially blood thinners.
- Avoid eating or drinking for a specified period before the procedure.
- Arrange for transportation home post-procedure due to sedation or anesthesia.
Recovery and Aftercare
Post-procedure recovery typically involves:
- Resting for a few hours in a recovery area.
- Monitoring for any immediate complications.
- Keeping the injection site clean and dry.
- Following up with prescribed medications for pain management.
Possible Complications
While generally safe, potential complications include:
- Infection at the injection site.
- Bleeding or hematoma formation.
- Nerve damage or pain at the site.
- Device malfunction or displacement.


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Learn morePost-Procedure Follow-Up
Follow-up care is essential for monitoring recovery:
- Initial follow-up within a week to assess the injection site.
- Regular check-ups to evaluate the effectiveness of the drug delivery system.
- Adjustments to medication dosages as needed.
Alternative Treatments
Patients may consider these alternative treatments:
- Oral medications for pain management.
- Physical therapy to improve mobility and reduce pain.
- Nerve blocks or other injection therapies.
- Acupuncture or chiropractic care.
Home Care Tips
To aid recovery, patients should consider the following tips:
- Keep the injection site clean and dry.
- Avoid strenuous activities for a few days.
- Take prescribed medications as directed.
- Monitor for signs of infection or complications.
Patient Education & Prevention
To prevent recurrence, patients should focus on:
- Adhering to prescribed treatment plans.
- Engaging in regular physical activity as tolerated.
- Maintaining a healthy diet to support overall health.
- Regularly communicating with healthcare providers about symptoms.
Billing and Coding Information
CPT Code: 21198
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- LT - Left side
- RT - Right side
Average Cost and Insurance Coverage
The cost of this procedure can vary widely:
- Average cost ranges from $5,000 to $15,000 depending on the complexity.
- Insurance coverage typically includes this procedure if deemed medically necessary.
- Patients should verify coverage details with their insurance provider.
Related CPT Codes
References and Sources