Overview of CPT Code 21188: Injection of bone cement into vertebral body
CPT Code 21188 refers to the procedure of injecting bone cement into a vertebral body to stabilize fractures or lesions, commonly used in conditions like osteoporosis.
When CPT Code 21188 is Used?
This procedure is indicated in various clinical scenarios.
- Vertebral compression fractures due to osteoporosis
- Pathological fractures from tumors
- Pain management in patients with vertebral lesions
- Spinal instability requiring augmentation
Symptoms Indicating This Procedure
Patients may report specific symptoms that lead to this procedure.
- Severe back pain
- Limited mobility or difficulty in movement
- Numbness or tingling in the legs
- Loss of height or spinal deformity
Causes and Risk Factors
Understanding the causes and risk factors is crucial for prevention.
- Osteoporosis or low bone density
- Age-related bone weakening
- Previous spinal injuries
- Certain cancers that affect bone health
Diagnostic Tests Before Procedure
Several tests may be conducted to confirm the need for this procedure.
- X-rays of the spine
- MRI to assess soft tissue and bone involvement
- CT scans for detailed imaging of vertebrae
- Bone density tests to evaluate osteoporosis
Procedure Description
The procedure involves several key steps.
- Patient is positioned comfortably, often lying on their stomach.
- Local anesthesia is administered to numb the area.
- A small incision is made to access the vertebral body.
- Bone cement is injected into the vertebra under fluoroscopic guidance.
- The incision is closed, and the patient is monitored.
Preparation for the Procedure
Patients should follow specific guidelines before the procedure.
- Discuss all medications with the healthcare provider.
- Avoid blood thinners for a specified period before the procedure.
- Arrange for transportation post-procedure due to sedation.
- Follow fasting instructions if sedation is planned.
Recovery and Aftercare
Post-procedure care is essential for recovery.
- Rest for the first few days post-procedure.
- Gradually resume normal activities as advised by the physician.
- Follow up for any signs of complications.
- Pain management with prescribed medications.
Possible Complications
While generally safe, there are potential risks involved.
- Infection at the injection site
- Allergic reaction to the cement
- Nerve damage or spinal cord injury
- Cement leakage into surrounding tissues


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Learn morePost-Procedure Follow-Up
Regular follow-up is important for monitoring recovery.
- Initial follow-up within one week post-procedure.
- Subsequent visits at one month and three months.
- Imaging studies may be repeated to assess healing.
- Ongoing evaluation of pain and mobility.
Alternative Treatments
There are non-surgical options available.
- Physical therapy to strengthen back muscles
- Pain management with medications
- Bracing to support the spine
- Vertebroplasty or kyphoplasty as alternative surgical options
Home Care Tips
Patients can take steps at home to aid recovery.
- Use ice packs to reduce swelling and pain.
- Engage in gentle stretching and mobility exercises.
- Maintain a healthy diet rich in calcium and vitamin D.
- Avoid heavy lifting and strenuous activities.
Patient Education & Prevention
Education is key to preventing future issues.
- Understand the importance of bone health.
- Engage in weight-bearing exercises.
- Regular screenings for osteoporosis.
- Avoid smoking and limit alcohol consumption.
Billing and Coding Information
CPT Code: 21188
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- LT - Left side
- RT - Right side
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $5,000 to $15,000.
- Insurance may cover the procedure if deemed medically necessary.
- Out-of-pocket costs depend on the insurance plan.
References and Sources