Overview of CPT Code 21183: Injection of bone marrow aspirate
CPT Code 21183 refers to the procedure of injecting bone marrow aspirate, which involves extracting bone marrow from a donor site and injecting it into a specific area to promote healing or regeneration of tissue.
When CPT Code 21183 is Used?
This procedure is indicated in various clinical scenarios.
- Treatment of osteonecrosis or avascular necrosis of the bone.
- Management of chronic non-union fractures.
- Support for bone regeneration in orthopedic surgeries.
- Enhancement of healing in joint or cartilage injuries.
Symptoms Indicating This Procedure
Patients may report several symptoms that lead to the consideration of this procedure.
- Persistent pain in the affected bone or joint.
- Swelling or inflammation around the injury site.
- Limited range of motion in the affected area.
- Signs of bone degeneration on imaging studies.
Causes and Risk Factors
Understanding the underlying causes and risk factors is crucial for identifying candidates for this procedure.
- Previous trauma or injury to the bone.
- Chronic conditions such as osteoporosis.
- Certain autoimmune diseases affecting bone health.
- Genetic predispositions to bone disorders.
Diagnostic Tests Before Procedure
Several diagnostic tests may be performed to assess the need for this procedure.
- X-rays to evaluate bone structure and integrity.
- MRI scans to assess soft tissue and bone marrow conditions.
- CT scans for detailed imaging of complex fractures.
- Blood tests to rule out infections or other underlying conditions.
Procedure Description
The procedure involves several key steps to ensure safety and effectiveness.
- Patient is positioned comfortably and the donor site is identified.
- Local anesthesia is administered to minimize discomfort.
- Bone marrow is aspirated from the iliac crest or another site.
- The aspirate is processed and prepared for injection.
- The prepared bone marrow is injected into the target area.
Preparation for the Procedure
Proper preparation is essential for a successful procedure.
- Discuss any medications with your healthcare provider.
- Avoid blood thinners or anti-inflammatory medications as advised.
- Arrive at the facility with a responsible adult for post-procedure transport.
- Wear comfortable clothing and follow any fasting instructions if applicable.
Recovery and Aftercare
Post-procedure care is important for optimal recovery.
- Rest the affected area and avoid strenuous activities for a few days.
- Apply ice to reduce swelling and discomfort.
- Follow prescribed pain management protocols.
- Attend follow-up appointments to monitor healing progress.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Infection at the injection or aspiration site.
- Bleeding or hematoma formation.
- Nerve or tissue damage near the injection site.
- Allergic reactions to anesthesia or other materials used.


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Learn morePost-Procedure Follow-Up
Monitoring after the procedure is crucial for assessing recovery.
- Initial follow-up within one week to check for complications.
- Subsequent visits at 2-4 weeks to evaluate healing.
- Long-term follow-up as needed based on recovery progress.
Alternative Treatments
There are several non-surgical options available for managing similar conditions.
- Physical therapy to strengthen surrounding muscles.
- Medications for pain management and inflammation.
- Corticosteroid injections to reduce inflammation.
- Platelet-rich plasma (PRP) therapy for tissue healing.
Home Care Tips
Patients can take several steps at home to aid recovery.
- Keep the injection site clean and dry.
- Monitor for signs of infection such as increased redness or swelling.
- Stay hydrated and maintain a balanced diet to support healing.
- Engage in gentle movements as advised by your healthcare provider.
Patient Education & Prevention
Educating patients on prevention can help avoid recurrence.
- Maintain a healthy lifestyle with regular exercise.
- Avoid high-impact activities if at risk for bone injuries.
- Manage chronic conditions effectively to support bone health.
- Regular check-ups to monitor bone density and health.
Billing and Coding Information
CPT Code: 21183
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- LT - Left side
- RT - Right side
Average Cost and Insurance Coverage
Costs can vary based on location and insurance coverage.
- Average cost ranges from $1,500 to $3,000.
- Insurance may cover the procedure if deemed medically necessary.
- Check with your insurance provider for specific coverage details.
Related CPT Codes
References and Sources