Overview of CPT Code 21182: Injection of implantable drug delivery device
CPT Code 21182 refers to the procedure involving the injection of an implantable drug delivery device, which is used to administer medication directly into a specific area of the body over an extended period.
When CPT Code 21182 is Used?
This procedure is indicated in various clinical scenarios.
- Chronic pain management requiring long-term medication delivery.
- Treatment of certain cancers where localized drug delivery is beneficial.
- Management of severe spasticity or muscle disorders.
- Conditions requiring continuous infusion of medication for effective control.
Symptoms Indicating This Procedure
Patients may present with specific symptoms that warrant this procedure.
- Persistent pain not relieved by oral medications.
- Severe muscle spasms or spasticity.
- Symptoms of localized disease that may benefit from targeted therapy.
- Need for consistent medication levels in chronic conditions.
Causes and Risk Factors
Several factors may lead to the need for an implantable drug delivery device.
- Chronic pain conditions such as fibromyalgia or arthritis.
- Neurological disorders like multiple sclerosis.
- Certain types of cancer requiring localized treatment.
- Previous unsuccessful treatments with oral medications.
Diagnostic Tests Before Procedure
Prior to the procedure, specific diagnostic tests may be conducted.
- Imaging studies such as MRI or CT scans to assess the target area.
- Blood tests to evaluate overall health and medication levels.
- Nerve conduction studies if neurological issues are present.
- Pain assessments to determine the severity and location of symptoms.
Procedure Description
The procedure involves several key steps to ensure safety and effectiveness.
- Patient is positioned comfortably and the area is cleaned and sterilized.
- Local anesthesia is administered to minimize discomfort.
- A small incision is made to insert the drug delivery device.
- The device is placed in the appropriate location and secured.
- The incision is closed and dressed appropriately.
Preparation for the Procedure
Patients should follow specific guidelines before the procedure.
- Discuss all medications with the healthcare provider, including over-the-counter drugs.
- Avoid blood thinners or anti-inflammatory medications as advised.
- Arrive fasting if instructed, especially if sedation is planned.
- Arrange for transportation home post-procedure.
Recovery and Aftercare
Post-procedure care is crucial for optimal recovery.
- Rest for the first 24 hours and avoid strenuous activities.
- Keep the incision site clean and dry; follow dressing change instructions.
- Monitor for signs of infection such as increased redness or discharge.
- Follow up with the healthcare provider for device checks and medication adjustments.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Infection at the insertion site.
- Device malfunction or displacement.
- Allergic reactions to the medication or device materials.
- Nerve damage or pain at the insertion site.


Secure, compliant, and built for trust
HIPAA-compliant and designed with privacy in mind, your patient’s data is protected. Focus on care while we safeguard your information.
Learn morePost-Procedure Follow-Up
Regular follow-up is essential for monitoring the device and patient health.
- Initial follow-up within one week to assess the incision site.
- Regular check-ups every few months to evaluate device function.
- Adjustments to medication dosages based on patient response.
- Long-term monitoring for any complications or side effects.
Alternative Treatments
There are several non-surgical options available for managing symptoms.
- Oral medications for pain management.
- Physical therapy to improve mobility and reduce pain.
- Nerve blocks or injections for localized pain relief.
- Transcutaneous electrical nerve stimulation (TENS) therapy.
Home Care Tips
Patients can take steps at home to aid recovery.
- Follow all post-operative care instructions provided by the healthcare team.
- Use ice packs to reduce swelling if recommended.
- Stay hydrated and maintain a balanced diet to support healing.
- Engage in light activities as tolerated, avoiding heavy lifting.
Patient Education & Prevention
Education is key to preventing complications and recurrence.
- Understand the importance of medication adherence.
- Recognize signs of complications early and seek help.
- Maintain regular follow-up appointments for device monitoring.
- Discuss lifestyle changes that may improve overall health.
Billing and Coding Information
CPT Code: 21182
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- LT - Left side
- RT - Right side
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $5,000 to $15,000 depending on the device and facility.
- Most insurance plans cover the procedure if deemed medically necessary.
- Out-of-pocket costs may apply depending on the patient's insurance plan.
Related CPT Codes
References and Sources