Overview of CPT Code 21121: Excision of benign lesion, face, ears, scalp, neck
CPT Code 21121 refers to the surgical excision of benign lesions located on the face, ears, scalp, or neck. This procedure is typically performed to remove non-cancerous growths that may cause cosmetic concerns or discomfort.
When CPT Code 21121 is Used?
This code is applicable in various clinical scenarios.
- Removal of benign tumors such as lipomas or seborrheic keratosis.
- Excision of cysts that are symptomatic or cosmetically undesirable.
- Surgical intervention for lesions that are growing or changing in appearance.
Symptoms Indicating This Procedure
Patients may report several symptoms that warrant this procedure.
- Visible growths on the skin that are changing in size or color.
- Pain or discomfort associated with the lesion.
- Itching or irritation in the area of the lesion.
Causes and Risk Factors
Several factors can contribute to the development of benign lesions.
- Genetic predisposition to skin growths.
- Sun exposure leading to skin changes.
- Hormonal changes that may influence skin growth.
Diagnostic Tests Before Procedure
Certain tests may be conducted to confirm the need for excision.
- Physical examination of the lesion.
- Dermatoscopy to assess the characteristics of the lesion.
- Biopsy if there is uncertainty about the nature of the lesion.
Procedure Description
The excision procedure follows a systematic approach.
- Patient is positioned comfortably and the area is cleaned.
- Local anesthesia is administered to numb the area.
- The surgeon makes an incision around the lesion.
- The lesion is carefully excised along with a margin of healthy tissue.
- The incision is closed with sutures or adhesive strips.
Preparation for the Procedure
Patients should follow specific guidelines before the procedure.
- Avoid blood thinners and certain medications as advised by the physician.
- Do not eat or drink for a specified period before the procedure if sedation is planned.
- Arrive at the facility with clean skin and avoid applying lotions or makeup.
Recovery and Aftercare
Post-procedure care is crucial for optimal healing.
- Expect some swelling and discomfort for a few days.
- Keep the area clean and dry; follow wound care instructions.
- Take prescribed pain medications as needed.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Infection at the site of excision.
- Scarring or changes in skin pigmentation.
- Recurrence of the lesion if not completely excised.


Secure, compliant, and built for trust
HIPAA-compliant and designed with privacy in mind, your patient’s data is protected. Focus on care while we safeguard your information.
Learn morePost-Procedure Follow-Up
Follow-up visits are important for monitoring recovery.
- Schedule a follow-up appointment within 1-2 weeks to check the healing process.
- Monitor for any signs of infection or complications.
- Discuss pathology results if a biopsy was performed.
Alternative Treatments
There are non-surgical options available for managing benign lesions.
- Topical treatments for superficial lesions.
- Cryotherapy to freeze off certain types of lesions.
- Laser therapy for cosmetic concerns.
Home Care Tips
Patients can take steps at home to aid recovery.
- Keep the surgical site clean and dry.
- Avoid strenuous activities that may stress the incision.
- Follow all post-operative instructions provided by the healthcare provider.
Patient Education & Prevention
Educating patients can help prevent recurrence.
- Regular skin checks for new or changing lesions.
- Use sunscreen to protect skin from UV damage.
- Maintain a healthy lifestyle to support skin health.
Billing and Coding Information
CPT Code: 21121
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- RT - Right side
- LT - Left side
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $200 to $1,500 depending on complexity.
- Most insurance plans cover the procedure if deemed medically necessary.
- Out-of-pocket costs may apply depending on the insurance policy.
Related CPT Codes
- 11400 - Excision, benign skin lesion, face, ears, scalp, neck; excised diameter over 4.0 cm.
- 11401 - Excision, benign skin lesion, face, ears, scalp, neck; excised diameter over 4.0 cm.
- 11402 - Excision, benign skin lesion, face, ears, scalp, neck; excised diameter over 4.0 cm.
- 11403 - Excision, benign skin lesion, face, ears, scalp; excised diameter over 4.0 cm.
- 11406 - Excision, benign skin lesion; face, ears, scalp, neck, excised diameter over 4.0 cm
References and Sources