Overview of CPT Code 20987: Injection of Biologic Agent into Joint or Bursa
CPT Code 20987 refers to the injection of a biologic agent directly into a joint or bursa to alleviate pain and inflammation associated with various musculoskeletal conditions.
When CPT Code 20987 is Used?
This procedure is indicated in several clinical scenarios.
- Osteoarthritis of the knee, hip, or shoulder.
- Rheumatoid arthritis exacerbations.
- Tendinitis or bursitis that has not responded to conservative treatments.
- Joint pain due to inflammatory conditions.
Symptoms Indicating This Procedure
Patients may report various symptoms that lead to this procedure.
- Persistent joint pain that limits daily activities.
- Swelling and inflammation around the joint.
- Stiffness, especially in the morning or after periods of inactivity.
- Reduced range of motion in the affected joint.
Causes and Risk Factors
Understanding the underlying causes can help in managing the condition.
- Age-related wear and tear on joints.
- Previous joint injuries or trauma.
- Genetic predisposition to joint diseases.
- Obesity, which increases stress on weight-bearing joints.
Diagnostic Tests Before Procedure
Several tests may be conducted to confirm the need for this injection.
- X-rays to assess joint damage.
- MRI to evaluate soft tissue structures.
- Ultrasound to guide injection and assess joint effusion.
- Blood tests to rule out systemic inflammatory diseases.
Procedure Description
The injection procedure is typically straightforward.
- The patient is positioned comfortably, and the skin over the injection site is cleaned.
- A local anesthetic may be applied to minimize discomfort.
- Using a sterile syringe, the biologic agent is injected into the joint or bursa.
- The injection site is bandaged, and the patient is monitored briefly.
Preparation for the Procedure
Patients should follow specific guidelines before the injection.
- Inform the physician about any allergies, especially to medications.
- Avoid blood thinners or anti-inflammatory medications for a few days prior.
- Wear loose-fitting clothing to allow easy access to the injection site.
- Arrange for transportation if sedation is used.
Recovery and Aftercare
Post-procedure care is essential for optimal recovery.
- Rest the joint for 24-48 hours after the injection.
- Apply ice to reduce swelling and discomfort.
- Follow up with prescribed medications, if any.
- Gradually resume normal activities as tolerated.
Possible Complications
While generally safe, there are potential risks involved.
- Infection at the injection site.
- Allergic reaction to the injected substance.
- Temporary increase in pain or swelling.
- Bleeding or bruising at the injection site.


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Learn morePost-Procedure Follow-Up
Monitoring after the procedure is crucial.
- Schedule a follow-up appointment within 1-2 weeks.
- Report any unusual symptoms, such as fever or increased pain.
- Discuss the effectiveness of the injection and any further treatment options.
Alternative Treatments
There are several non-surgical options available.
- Physical therapy to strengthen surrounding muscles.
- Oral anti-inflammatory medications.
- Corticosteroid injections for immediate relief.
- Lifestyle modifications, including weight loss and exercise.
Home Care Tips
Simple tips can aid in recovery and comfort.
- Keep the injection site clean and dry.
- Avoid strenuous activities for a few days.
- Use ice packs to manage swelling.
- Stay hydrated and maintain a balanced diet.
Patient Education & Prevention
Educating patients can help prevent recurrence.
- Engage in regular low-impact exercise to maintain joint health.
- Maintain a healthy weight to reduce joint stress.
- Consider dietary supplements like glucosamine and chondroitin.
- Stay informed about joint health and seek early treatment for symptoms.
Billing and Coding Information
CPT Code: 20987
Category: Surgery
Common Modifiers:
- 50 - Bilateral procedure
- RT - Right side
- LT - Left side
Average Cost and Insurance Coverage
Costs can vary based on location and insurance.
- Average cost ranges from $300 to $800 per injection.
- Many insurance plans cover the procedure, but prior authorization may be required.
- Out-of-pocket costs depend on the patient's deductible and copayment.
Related CPT Codes
References and Sources