Overview of CPT Code 20527:'Injection into a major joint or bursa'
CPT Code 20527 refers to the injection of a therapeutic substance into a major joint or bursa, such as the knee, hip, or shoulder. This procedure is commonly used to relieve pain and inflammation associated with various musculoskeletal conditions.
When CPT Code 20527 is Used?
This code is applicable in several clinical scenarios, including:
- Osteoarthritis of the knee or hip
- Rheumatoid arthritis flare-ups
- Bursitis in the shoulder or hip
- Tendinitis affecting major joints
- Joint effusion requiring aspiration and injection
Symptoms Indicating This Procedure
Patients may report various symptoms that lead to the consideration of this injection, including:
- Persistent joint pain during movement or at rest
- Swelling and tenderness around the joint
- Stiffness, especially in the morning or after inactivity
- Limited range of motion in the affected joint
- Pain that worsens with activity
Causes and Risk Factors
Several factors can contribute to the need for a joint injection, including:
- Age-related degeneration of joint tissues
- Previous joint injuries or trauma
- Chronic inflammatory conditions like rheumatoid arthritis
- Obesity, which increases stress on weight-bearing joints
- Genetic predisposition to joint diseases
Diagnostic Tests Before Procedure
Before performing the injection, healthcare providers may utilize various diagnostic tests, including:
- X-rays to assess joint structure and degeneration
- MRI to evaluate soft tissue and cartilage damage
- Ultrasound to visualize joint effusion
- Blood tests to rule out systemic inflammatory conditions
Procedure Description
The injection procedure typically follows these steps:
- Patient is positioned comfortably, and the affected joint is exposed.
- Skin is cleaned with an antiseptic solution to prevent infection.
- A local anesthetic may be administered to minimize discomfort.
- A syringe containing the therapeutic agent is prepared.
- The needle is carefully inserted into the joint space or bursa.
- The medication is injected, and the needle is withdrawn.
- Pressure is applied to the injection site, and a bandage may be placed.
Preparation for the Procedure
Patients should follow these guidelines before the injection:
- Inform the doctor about any allergies, especially to medications.
- Discuss current medications, including blood thinners.
- Avoid taking anti-inflammatory medications for a few days prior.
- Wear loose-fitting clothing to allow easy access to the joint.
- Arrange for transportation if sedation is used.
Recovery and Aftercare
Post-procedure care is essential for optimal recovery:
- Rest the joint for 24-48 hours after the injection.
- Apply ice to the injection site to reduce swelling.
- Avoid strenuous activities for a few days.
- Follow any prescribed medication regimen for pain management.
- Attend follow-up appointments to monitor progress.
Possible Complications
While generally safe, this procedure may have risks, including:
- Infection at the injection site
- Bleeding or bruising
- Temporary increase in pain or swelling
- Allergic reaction to the injected substance
- Damage to surrounding structures


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Learn morePost-Procedure Follow-Up
Monitoring after the procedure is crucial:
- Schedule a follow-up visit within 1-2 weeks.
- Report any unusual symptoms, such as fever or increased pain.
- Discuss the effectiveness of the injection and any further treatment options.
- Regular check-ups may be needed for chronic conditions.
Alternative Treatments
Patients may consider these non-surgical options:
- Physical therapy to strengthen surrounding muscles.
- Oral anti-inflammatory medications.
- Corticosteroid pills for systemic inflammation.
- Hyaluronic acid injections as an alternative to corticosteroids.
- Acupuncture or chiropractic care for pain relief.
Home Care Tips
Patients can follow these tips for better recovery:
- Keep the injection site clean and dry.
- Use ice packs to manage swelling.
- Engage in gentle range-of-motion exercises as tolerated.
- Stay hydrated and maintain a balanced diet.
- Monitor for any signs of infection or complications.
Patient Education & Prevention
Educating patients can help prevent recurrence:
- Maintain a healthy weight to reduce joint stress.
- Engage in regular low-impact exercise to strengthen joints.
- Avoid repetitive stress on joints during activities.
- Consider joint supplements after consulting a healthcare provider.
- Stay informed about joint health and seek early treatment for symptoms.
Billing and Coding Information
CPT Code: 20527
Category: Surgery
Common Modifiers:
- 50 - Bilateral procedure
- RT - Right side
- LT - Left side
Average Cost and Insurance Coverage
Costs can vary based on location and insurance:
- Average cost ranges from $200 to $800 per injection.
- Many insurance plans cover the procedure with prior authorization.
- Out-of-pocket costs may apply depending on the deductible.
- Check with your insurance provider for specific coverage details.
Related CPT Codes
References and Sources