Overview of CPT Code 20220:'Biopsy, soft tissue, superficial'
CPT Code 20220 refers to a procedure for obtaining a biopsy of superficial soft tissue. This procedure is typically performed to diagnose various skin conditions, including tumors, infections, or inflammatory diseases.
When CPT Code 20220 is Used?
This code is used in specific clinical scenarios where a biopsy is necessary.
- Suspicious skin lesions that may be cancerous.
- Persistent skin rashes that do not respond to treatment.
- Unexplained lumps or masses in the skin.
- Infections that require tissue sampling for diagnosis.
Symptoms Indicating This Procedure
Patients may report various symptoms that lead to the need for a biopsy.
- New or changing moles or skin lesions.
- Itching or pain in a specific area of the skin.
- Swelling or redness around a lump.
- Non-healing sores or ulcers.
Causes and Risk Factors
Several factors can contribute to the need for a superficial soft tissue biopsy.
- Family history of skin cancer.
- Excessive sun exposure.
- Weakened immune system.
- Previous skin conditions or lesions.
Diagnostic Tests Before Procedure
Certain tests may be conducted prior to the biopsy to guide the procedure.
- Physical examination of the skin.
- Dermatoscopy to examine skin lesions.
- Imaging studies like ultrasound if deeper structures are involved.
Procedure Description
The biopsy procedure involves several key steps.
- The area is cleaned and sterilized.
- Local anesthesia is administered to minimize discomfort.
- A small incision is made to remove a sample of the tissue.
- The sample is sent to a laboratory for analysis.
- The incision is closed with sutures or adhesive.
Preparation for the Procedure
Patients should follow specific guidelines before undergoing the biopsy.
- Avoid blood thinners for a few days prior to the procedure.
- Inform the doctor about any allergies or medications.
- Arrive with clean skin, free of lotions or creams.
Recovery and Aftercare
Post-procedure care is essential for proper healing.
- Keep the biopsy site clean and dry.
- Change dressings as instructed by the healthcare provider.
- Avoid strenuous activities for a few days.
- Monitor for signs of infection, such as increased redness or discharge.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Infection at the biopsy site.
- Excessive bleeding.
- Scarring or changes in skin pigmentation.
- Allergic reactions to anesthesia.


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Learn morePost-Procedure Follow-Up
Follow-up appointments are crucial for monitoring recovery.
- Schedule a follow-up visit within one to two weeks.
- Review biopsy results with the healthcare provider.
- Discuss any ongoing symptoms or concerns.
Alternative Treatments
In some cases, non-invasive options may be considered.
- Topical treatments for skin conditions.
- Cryotherapy for certain skin lesions.
- Phototherapy for inflammatory skin diseases.
Home Care Tips
Patients can take steps at home to aid recovery.
- Keep the biopsy site clean and avoid touching it.
- Use over-the-counter pain relief as needed.
- Stay hydrated and maintain a balanced diet.
Patient Education & Prevention
Educating patients can help prevent future issues.
- Regular skin checks for new or changing lesions.
- Use sunscreen to protect against UV damage.
- Avoid tanning beds and excessive sun exposure.
Billing and Coding Information
CPT Code: 20220
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- LT - Left side
- RT - Right side
Average Cost and Insurance Coverage
Costs can vary based on location and insurance.
- Average cost ranges from $200 to $1,000.
- Most insurance plans cover medically necessary biopsies.
- Check with your insurance provider for specific coverage details.
Related CPT Codes
References and Sources