Overview of CPT Code 19121: Breast Biopsy, Needle, Percutaneous
CPT Code 19121 refers to a percutaneous needle biopsy of the breast, a minimally invasive procedure used to obtain tissue samples for diagnostic evaluation of breast abnormalities.
When CPT Code 19121 is Used?
This procedure is indicated in various clinical scenarios.
- Suspicious breast mass detected on imaging studies.
- Abnormal findings on a clinical breast exam.
- Follow-up of previously identified breast lesions.
- Assessment of breast tissue in patients with a family history of breast cancer.
Symptoms Indicating This Procedure
Patients may report several symptoms that warrant a biopsy.
- Palpable lump or mass in the breast.
- Changes in breast shape or size.
- Nipple discharge that is bloody or clear.
- Skin changes over the breast, such as dimpling or redness.
Causes and Risk Factors
Several factors can contribute to the need for a breast biopsy.
- Family history of breast cancer.
- Genetic mutations such as BRCA1 or BRCA2.
- Previous breast biopsies with atypical results.
- Age, with increased risk in women over 40.
Diagnostic Tests Before Procedure
Prior to the biopsy, certain tests may be performed.
- Mammography to identify abnormalities.
- Ultrasound to evaluate breast masses.
- MRI for detailed imaging of breast tissue.
- Fine needle aspiration cytology if indicated.
Procedure Description
The procedure involves several key steps.
- Patient is positioned comfortably, usually lying on their back.
- The area of the breast is cleaned and sterilized.
- Local anesthesia is administered to numb the area.
- A thin needle is inserted into the breast to obtain tissue samples.
- Multiple samples may be taken to ensure adequate tissue for diagnosis.
- The needle is removed, and pressure is applied to minimize bleeding.
Preparation for the Procedure
Patients should follow specific guidelines before the biopsy.
- Avoid blood thinners for several days prior to the procedure.
- Inform the doctor of any allergies, especially to anesthetics.
- Wear comfortable clothing and avoid wearing deodorant or lotions on the day of the procedure.
- Arrange for someone to drive you home if sedation is used.
Recovery and Aftercare
Post-procedure care is essential for recovery.
- Rest for the remainder of the day after the procedure.
- Apply ice packs to the area to reduce swelling.
- Keep the biopsy site clean and dry for a few days.
- Follow up with the doctor for results and further instructions.
Possible Complications
While generally safe, there are potential risks.
- Bleeding at the biopsy site.
- Infection at the site of the procedure.
- Hematoma formation.
- Discomfort or pain in the breast area.


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Learn morePost-Procedure Follow-Up
Monitoring after the procedure is important.
- Schedule a follow-up appointment within a week to discuss results.
- Monitor for any signs of infection or excessive bleeding.
- Follow up with imaging studies if recommended by the physician.
Alternative Treatments
There are non-surgical options available.
- Watchful waiting for benign findings.
- Medication management for hormonal imbalances.
- Regular imaging follow-ups to monitor changes.
Home Care Tips
Patients can take steps to aid recovery at home.
- Avoid strenuous activities for a few days.
- Take over-the-counter pain relievers as needed.
- Keep the biopsy site clean and dry.
- Monitor for any unusual symptoms and contact your doctor if they occur.
Patient Education & Prevention
Education is key to prevention and early detection.
- Perform regular breast self-exams.
- Schedule routine mammograms as recommended.
- Discuss family history with your healthcare provider.
- Maintain a healthy lifestyle to reduce breast cancer risk.
Billing and Coding Information
CPT Code: 19121
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- RT - Right side
- LT - Left side
Average Cost and Insurance Coverage
Costs can vary based on location and insurance.
- Average cost ranges from $1,000 to $3,000.
- Most insurance plans cover the procedure if deemed medically necessary.
- Check with your insurance provider for specific coverage details.
Related CPT Codes
References and Sources