Overview of CPT Code 16035:Application of skin substitute graft
CPT Code 16035 refers to the application of a skin substitute graft, which is a medical procedure used to cover and promote healing in areas of skin loss or damage. This procedure is often utilized in cases of chronic wounds, burns, or surgical defects.
When CPT Code 16035 is Used?
This procedure is indicated in various clinical scenarios.
- Chronic non-healing wounds such as diabetic ulcers.
- Acute wounds resulting from trauma or surgery.
- Burn injuries requiring skin coverage.
- Skin loss due to infections or other dermatological conditions.
Symptoms Indicating This Procedure
Patients may present with specific symptoms that warrant this procedure.
- Persistent pain or discomfort in the affected area.
- Visible skin loss or open wounds.
- Signs of infection such as redness, swelling, or discharge.
- Delayed healing despite standard wound care.
Causes and Risk Factors
Understanding the underlying causes and risk factors is crucial for prevention.
- Diabetes mellitus leading to poor circulation.
- Peripheral vascular disease.
- Obesity, which can impair healing.
- History of radiation therapy affecting skin integrity.
Diagnostic Tests Before Procedure
Certain tests may be conducted to assess the need for this procedure.
- Wound cultures to identify infections.
- Blood tests to evaluate overall health and healing capacity.
- Imaging studies to assess the extent of tissue damage.
Procedure Description
The application of a skin substitute graft involves several key steps.
- Preparation of the wound site by cleaning and debriding as necessary.
- Selection of an appropriate skin substitute based on the wound characteristics.
- Application of the skin substitute to the wound area.
- Securing the graft in place with sutures or adhesive as needed.
- Dressing the area to protect the graft and promote healing.
Preparation for the Procedure
Patients should follow specific guidelines to prepare for the procedure.
- Avoid smoking and alcohol consumption prior to the procedure.
- Inform the healthcare provider of any medications being taken.
- Follow any dietary restrictions as advised.
- Arrive with clean skin and avoid applying lotions or creams.
Recovery and Aftercare
Post-procedure care is essential for optimal recovery.
- Monitor the graft site for signs of infection.
- Keep the area clean and dry as instructed.
- Avoid strenuous activities that may stress the graft.
- Follow up with the healthcare provider for wound assessment.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Infection at the graft site.
- Graft failure or rejection.
- Scarring or changes in skin pigmentation.
- Delayed healing or complications related to underlying conditions.


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Learn morePost-Procedure Follow-Up
Regular follow-up is important to ensure proper healing.
- Initial follow-up within one week post-procedure.
- Subsequent visits as needed based on healing progress.
- Assessment of graft integration and overall wound healing.
Alternative Treatments
There are non-surgical options available for wound management.
- Advanced wound dressings to promote healing.
- Negative pressure wound therapy.
- Topical growth factors or skin substitutes.
- Physical therapy to improve circulation and healing.
Home Care Tips
Patients can take steps at home to support recovery.
- Keep the graft site clean and dry.
- Avoid tight clothing that may irritate the area.
- Stay hydrated and maintain a balanced diet.
- Report any unusual symptoms to the healthcare provider promptly.
Patient Education & Prevention
Education is key to preventing future skin issues.
- Manage chronic conditions like diabetes effectively.
- Practice good skin hygiene and care.
- Avoid injuries to the skin and seek prompt treatment for wounds.
- Regularly monitor skin health, especially in high-risk individuals.
Billing and Coding Information
CPT Code: 16035
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- 59 - Distinct procedural service
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $1,500 to $3,500.
- Insurance may cover the procedure if deemed medically necessary.
- Out-of-pocket costs depend on the patient's insurance plan.
References and Sources