Overview of CPT Code 15981: Skin Graft, Full Thickness
CPT Code 15981 refers to the surgical procedure of a full-thickness skin graft, which involves the removal of skin from a donor site and its transplantation to a recipient site to promote healing and restore skin integrity.
When CPT Code 15981 is Used?
This procedure is indicated in various clinical scenarios.
- Severe skin loss due to trauma or injury.
- Chronic non-healing wounds.
- Surgical excision of skin cancers.
- Burn injuries requiring skin replacement.
- Congenital skin defects.
Symptoms Indicating This Procedure
Patients may present with specific symptoms that necessitate a skin graft.
- Open wounds that do not heal.
- Significant skin loss or damage.
- Pain or discomfort in the affected area.
- Signs of infection in the wound.
- Visible scarring or deformity.
Causes and Risk Factors
Understanding the causes and risk factors can help in prevention and management.
- Traumatic injuries such as cuts or burns.
- Chronic conditions like diabetes that impair healing.
- Skin cancer requiring excision.
- Infections that lead to tissue loss.
- Poor circulation or vascular diseases.
Diagnostic Tests Before Procedure
Certain tests may be performed to assess the need for a skin graft.
- Physical examination of the wound.
- Imaging studies like ultrasound to assess tissue viability.
- Blood tests to evaluate overall health and healing capacity.
- Cultures to identify any underlying infections.
Procedure Description
The following steps outline the full-thickness skin graft procedure.
- Anesthesia is administered to ensure patient comfort.
- The donor site is selected and prepared.
- Full-thickness skin is excised from the donor site.
- The recipient site is prepared by removing unhealthy tissue.
- The graft is placed onto the recipient site and secured.
- Dressings are applied to protect the graft and promote healing.
Preparation for the Procedure
Patients should follow specific guidelines to prepare for the surgery.
- Consult with the surgeon about medications to avoid.
- Arrange for transportation to and from the procedure.
- Follow fasting instructions if applicable.
- Discuss any allergies or medical conditions with the healthcare team.
Recovery and Aftercare
Post-operative care is crucial for successful healing.
- Rest and limit physical activity for a few weeks.
- Keep the graft site clean and dry.
- Change dressings as instructed by the healthcare provider.
- Monitor for signs of infection such as increased redness or discharge.
- Follow up with the surgeon for wound assessment.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Infection at the graft or donor site.
- Graft failure or poor healing.
- Scarring at the donor or recipient site.
- Bleeding or hematoma formation.
- Nerve damage or altered sensation.


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Learn morePost-Procedure Follow-Up
Regular follow-up is essential to monitor healing.
- Initial follow-up within one week post-surgery.
- Subsequent visits every few weeks to assess graft integration.
- Long-term follow-up to monitor for complications or recurrence.
Alternative Treatments
There are non-surgical options that may be considered.
- Wound care management with advanced dressings.
- Negative pressure wound therapy.
- Skin substitutes or bioengineered skin products.
- Topical treatments to promote healing.
Home Care Tips
Patients can take steps at home to aid recovery.
- Keep the graft site clean and dry.
- Avoid strenuous activities that may stress the graft.
- Follow dietary recommendations to support healing.
- Stay hydrated and maintain a balanced diet.
Patient Education & Prevention
Education is key to preventing complications and recurrence.
- Understand the importance of wound care.
- Recognize signs of infection early.
- Manage underlying health conditions effectively.
- Avoid smoking to enhance healing.
Billing and Coding Information
CPT Code: 15981
Category: Surgical Procedures
Common Modifiers:
- 50 (bilateral procedure)
- RT (right side)
- LT (left side)
Average Cost and Insurance Coverage
Costs can vary based on several factors.
- Average cost ranges from $3,000 to $10,000.
- Insurance may cover the procedure if deemed medically necessary.
- Out-of-pocket costs depend on the insurance plan and deductible.
References and Sources