Overview of CPT Code 15792: Injection of Biologic Agent into Soft Tissue
CPT Code 15792 refers to the injection of a biologic agent into soft tissue, typically used to treat conditions such as tendonitis, bursitis, or other inflammatory conditions. This procedure aims to reduce inflammation and promote healing in affected areas.
When CPT Code 15792 is Used?
This code is applicable in various clinical scenarios where biologic agents are indicated.
- Chronic tendonitis in the shoulder or elbow
- Bursitis in the hip or knee
- Plantar fasciitis
- Soft tissue injuries requiring anti-inflammatory treatment
- Post-surgical recovery to enhance healing
Symptoms Indicating This Procedure
Patients may present with a variety of symptoms that warrant this procedure.
- Persistent pain in the affected joint or soft tissue
- Swelling and inflammation in the area
- Reduced range of motion
- Tenderness upon palpation
- Difficulty performing daily activities due to pain
Causes and Risk Factors
Understanding the underlying causes and risk factors can help in managing conditions treated with this procedure.
- Overuse injuries from repetitive activities
- Age-related degeneration of soft tissues
- Previous injuries or surgeries in the area
- Certain medical conditions like diabetes or rheumatoid arthritis
- Obesity, which can increase stress on joints
Diagnostic Tests Before Procedure
Several diagnostic tests may be performed to confirm the need for this injection.
- X-rays to rule out fractures or bone abnormalities
- MRI to assess soft tissue damage
- Ultrasound to visualize inflammation or fluid accumulation
- Blood tests to check for underlying inflammatory conditions
Procedure Description
The injection procedure is typically straightforward and performed in an outpatient setting.
- Patient is positioned comfortably, and the injection site is cleaned with antiseptic.
- Local anesthesia may be administered to minimize discomfort.
- The biologic agent is drawn into a syringe.
- The physician carefully injects the agent into the targeted soft tissue area.
- Post-injection, the site is bandaged, and the patient is monitored briefly.
Preparation for the Procedure
Proper preparation can enhance the effectiveness of the procedure.
- Discuss any medications with your physician, especially blood thinners.
- Avoid anti-inflammatory medications for a few days prior to the injection.
- Wear loose-fitting clothing to allow easy access to the injection site.
- Arrange for transportation if sedation is used during the procedure.
Recovery and Aftercare
Post-procedure care is essential for optimal recovery.
- Rest the affected area for at least 24 hours.
- Apply ice to reduce swelling and discomfort.
- Avoid strenuous activities for a few days.
- Follow up with your physician to monitor progress.
- Take prescribed medications as directed.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Infection at the injection site
- Allergic reaction to the biologic agent
- Increased pain or swelling post-injection
- Nerve or tissue damage if not performed correctly
- Bleeding or bruising at the injection site


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Learn morePost-Procedure Follow-Up
Regular follow-up is crucial to assess the effectiveness of the treatment.
- Initial follow-up within 1-2 weeks post-injection.
- Further assessments at 4-6 weeks to evaluate symptom improvement.
- Additional follow-ups may be scheduled based on recovery progress.
- Discuss any ongoing symptoms or concerns during visits.
Alternative Treatments
There are several non-surgical options available for managing soft tissue conditions.
- Physical therapy to strengthen and rehabilitate the area
- Corticosteroid injections for inflammation
- Oral anti-inflammatory medications
- Rest and ice therapy
- Acupuncture or massage therapy
Home Care Tips
Simple home care strategies can aid in recovery.
- Keep the injection site clean and dry.
- Use ice packs to manage swelling.
- Engage in gentle stretching exercises as advised.
- Maintain a healthy diet to support healing.
- Stay hydrated and get adequate rest.
Patient Education & Prevention
Educating patients on prevention can help avoid recurrence.
- Engage in regular exercise to maintain joint health.
- Use proper techniques during physical activities.
- Incorporate strength training to support soft tissues.
- Maintain a healthy weight to reduce joint stress.
- Seek early treatment for injuries to prevent chronic issues.
Billing and Coding Information
CPT Code: 15792
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- RT - Right side
- LT - Left side
Average Cost and Insurance Coverage
Costs can vary based on location and insurance coverage.
- Average cost ranges from $300 to $800 per injection.
- Insurance may cover the procedure if deemed medically necessary.
- Out-of-pocket costs depend on the patient's insurance plan.
- Pre-authorization may be required by some insurance providers.
Related CPT Codes
References and Sources