Overview of CPT Code 15789:Injection of Biologic Agent into Soft Tissue
CPT Code 15789 refers to the injection of a biologic agent into soft tissue, typically used to treat conditions such as inflammation, pain, or tissue degeneration. This procedure is often performed in outpatient settings and aims to promote healing and reduce symptoms.
When CPT Code 15789 is Used?
This procedure is indicated in various clinical scenarios.
- Chronic tendonitis or tendinopathy
- Osteoarthritis of joints
- Soft tissue injuries requiring enhanced healing
- Plantar fasciitis
- Bursitis
Symptoms Indicating This Procedure
Patients may report several symptoms that lead to this procedure.
- Persistent pain in the affected area
- Swelling and inflammation
- Reduced range of motion
- Tenderness upon palpation
- Difficulty performing daily activities
Causes and Risk Factors
Understanding the underlying causes can help in managing conditions effectively.
- Overuse injuries from repetitive activities
- Age-related degeneration of tissues
- Previous injuries or trauma
- Obesity, which increases joint stress
- Genetic predisposition to certain musculoskeletal conditions
Diagnostic Tests Before Procedure
Several tests may be conducted to confirm the need for this injection.
- X-rays to assess joint integrity
- MRI to evaluate soft tissue structures
- Ultrasound for real-time imaging of the injection site
- Blood tests to rule out infections or inflammatory conditions
Procedure Description
The injection procedure is straightforward and typically performed in an outpatient setting.
- Patient is positioned comfortably.
- The injection site is cleaned with antiseptic.
- Local anesthesia may be administered to minimize discomfort.
- The biologic agent is drawn into a syringe.
- The physician carefully injects the agent into the targeted soft tissue.
- Post-injection care instructions are provided.
Preparation for the Procedure
Proper preparation can enhance the effectiveness of the procedure.
- Discuss any medications with your physician, especially blood thinners.
- Avoid anti-inflammatory medications for a few days prior.
- Wear loose-fitting clothing to allow easy access to the injection site.
- Arrange for transportation if sedation is used.
Recovery and Aftercare
Post-procedure care is crucial for optimal recovery.
- Rest the affected area for 24-48 hours.
- Apply ice to reduce swelling.
- Avoid strenuous activities for a few days.
- Follow up with your physician as directed.
- Monitor for any signs of infection or unusual symptoms.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Infection at the injection site
- Allergic reaction to the biologic agent
- Increased pain or swelling post-injection
- Nerve or tissue damage
- Bleeding or bruising


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Learn morePost-Procedure Follow-Up
Regular follow-up is essential to monitor progress.
- Initial follow-up within 1-2 weeks post-injection.
- Assess pain levels and functional improvement.
- Further follow-ups may be scheduled based on recovery.
- Adjust treatment plans as necessary.
Alternative Treatments
There are several non-surgical options available.
- Physical therapy to strengthen and rehabilitate the area
- Corticosteroid injections for inflammation
- Oral anti-inflammatory medications
- Acupuncture for pain relief
- Bracing or splinting to immobilize the area
Home Care Tips
Simple home care can aid in recovery.
- Keep the injection site clean and dry.
- Use ice packs to manage swelling.
- Engage in gentle stretching exercises as tolerated.
- Stay hydrated and maintain a balanced diet.
- Follow all post-procedure instructions from your physician.
Patient Education & Prevention
Education is key to preventing recurrence.
- Understand the importance of proper body mechanics.
- Engage in regular exercise to maintain joint health.
- Avoid repetitive strain on affected areas.
- Maintain a healthy weight to reduce joint stress.
- Seek early treatment for injuries to prevent chronic issues.
Billing and Coding Information
CPT Code: 15789
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- 59 - Distinct procedural service
Average Cost and Insurance Coverage
Costs can vary based on location and insurance.
- Average cost ranges from $300 to $800 per injection.
- Insurance may cover the procedure if deemed medically necessary.
- Check with your insurance provider for specific coverage details.
Related CPT Codes
References and Sources