Overview of CPT Code 15782: Injection of Biologic Agent into Soft Tissue
CPT Code 15782 refers to the injection of a biologic agent into soft tissue, typically used to treat conditions such as tendonitis, bursitis, or other inflammatory conditions affecting soft tissues.
When CPT Code 15782 is Used?
This procedure is indicated in various clinical scenarios.
- Chronic tendonitis or tendinopathy
- Bursitis affecting mobility and causing pain
- Soft tissue injuries that have not responded to conservative treatments
- Inflammatory conditions such as rheumatoid arthritis affecting soft tissues
Symptoms Indicating This Procedure
Patients may report several symptoms that lead to the consideration of this injection.
- Persistent pain in the affected area
- Swelling and inflammation around the soft tissue
- Limited range of motion in the joint or affected area
- Tenderness to touch in the soft tissue region
Causes and Risk Factors
Understanding the underlying causes can help in managing the condition effectively.
- Overuse injuries from repetitive activities
- Age-related degeneration of soft tissues
- Previous injuries or trauma to the area
- Certain medical conditions like diabetes or autoimmune disorders
Diagnostic Tests Before Procedure
Several diagnostic tests may be performed to confirm the need for this injection.
- X-rays to rule out fractures or bone abnormalities
- MRI to assess soft tissue damage and inflammation
- Ultrasound to visualize the soft tissue and guide injection
- Blood tests to check for underlying inflammatory conditions
Procedure Description
The injection procedure is typically straightforward and performed in an outpatient setting.
- Patient is positioned comfortably, and the injection site is cleaned with antiseptic.
- Local anesthesia may be administered to minimize discomfort.
- The biologic agent is drawn into a syringe.
- Using ultrasound guidance, the physician locates the precise injection site.
- The biologic agent is injected into the soft tissue.
- The site is bandaged, and the patient is monitored briefly before discharge.
Preparation for the Procedure
Patients should follow specific guidelines to prepare for the injection.
- Inform the physician about any allergies, especially to medications.
- Avoid blood thinners or anti-inflammatory medications for a few days prior.
- Wear loose-fitting clothing to allow easy access to the injection site.
- Arrange for transportation if sedation is used during the procedure.
Recovery and Aftercare
Post-procedure care is essential for optimal recovery.
- Rest the affected area for at least 24 hours post-injection.
- Apply ice to reduce swelling and discomfort.
- Avoid strenuous activities for a few days.
- Follow up with the physician if symptoms worsen or do not improve.
Possible Complications
While generally safe, there are potential risks associated with the procedure.
- Infection at the injection site
- Allergic reaction to the biologic agent
- Increased pain or swelling after the injection
- Nerve or tissue damage if the injection is not performed correctly


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Learn morePost-Procedure Follow-Up
Monitoring after the procedure is crucial for assessing effectiveness.
- Schedule a follow-up appointment within 1-2 weeks post-injection.
- Monitor for any adverse reactions or complications.
- Assess pain levels and functional improvement during follow-up visits.
Alternative Treatments
There are several non-surgical options available for managing soft tissue conditions.
- Physical therapy to strengthen and rehabilitate the affected area
- Corticosteroid injections for inflammation control
- Oral anti-inflammatory medications
- Rest and activity modification to prevent further injury
Home Care Tips
Patients can take several steps at home to aid recovery.
- Keep the injection site clean and dry.
- Use ice packs to manage swelling and pain.
- Engage in gentle stretching and strengthening exercises as advised.
- Stay hydrated and maintain a balanced diet to support healing.
Patient Education & Prevention
Educating patients on prevention can help avoid recurrence.
- Understand proper body mechanics to prevent overuse injuries.
- Incorporate regular exercise to maintain flexibility and strength.
- Avoid repetitive motions that strain soft tissues.
- Seek early treatment for any signs of soft tissue injury.
Billing and Coding Information
CPT Code: 15782
Category: Surgical Procedures
Common Modifiers:
- 50 - Bilateral procedure
- RT - Right side
- LT - Left side
Average Cost and Insurance Coverage
Costs can vary based on location and insurance coverage.
- Average cost ranges from $300 to $800 per injection.
- Many insurance plans cover the procedure if deemed medically necessary.
- Patients should verify coverage with their insurance provider prior to the procedure.
Related CPT Codes
References and Sources