Overview of CPT Code 11100: Biopsy of skin, single lesion
CPT Code 11100 refers to the procedure of performing a biopsy on a single skin lesion. This procedure is essential for diagnosing various skin conditions, including skin cancers, infections, and inflammatory diseases.
When CPT Code 11100 is Used?
This code is applicable in several clinical scenarios.
- Suspicious skin lesions that may indicate malignancy.
- Persistent skin lesions that do not respond to treatment.
- Lesions with atypical features on physical examination.
- Skin lesions that require histological examination for diagnosis.
Symptoms Indicating This Procedure
Patients may report various symptoms prompting a biopsy.
- Changes in the color or size of a mole or skin lesion.
- Itching, bleeding, or oozing from a skin lesion.
- New growths on the skin that are concerning.
- Lesions that have an irregular border or surface.
Causes and Risk Factors
Understanding the causes and risk factors can help in prevention and early detection.
- Excessive sun exposure leading to skin damage.
- Family history of skin cancer.
- Weakened immune system due to conditions like HIV or medications.
- Previous history of skin cancer or atypical moles.
Diagnostic Tests Before Procedure
Certain tests may be conducted to guide the biopsy.
- Physical examination of the skin lesion.
- Dermatoscopy to visualize skin structures.
- Imaging studies if deeper lesions are suspected.
Procedure Description
The biopsy procedure involves several key steps.
- The area around the lesion is cleaned and sterilized.
- Local anesthesia is administered to minimize discomfort.
- A small section of the skin lesion is excised using a scalpel or punch tool.
- The sample is sent to a laboratory for histopathological analysis.
- The site is closed with sutures or adhesive strips as needed.
Preparation for the Procedure
Patients should follow specific guidelines before the biopsy.
- Avoid blood thinners like aspirin or ibuprofen a few days prior.
- Inform the doctor about any allergies or medications.
- Arrive with clean skin, avoiding lotions or creams on the biopsy site.
Recovery and Aftercare
Post-procedure care is crucial for healing.
- Keep the biopsy site clean and dry.
- Change the dressing as instructed by the healthcare provider.
- Avoid strenuous activities for a few days.
- Watch for signs of infection such as increased redness or pus.
Possible Complications
While generally safe, there are potential risks.
- Infection at the biopsy site.
- Excessive bleeding.
- Scarring or changes in skin pigmentation.
- Allergic reactions to anesthesia.


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Learn morePost-Procedure Follow-Up
Follow-up is essential to monitor healing and results.
- Schedule a follow-up appointment within 1-2 weeks.
- Discuss biopsy results and any further treatment if necessary.
- Monitor the biopsy site for any unusual changes.
Alternative Treatments
There are non-surgical options for skin lesions.
- Topical treatments for benign skin lesions.
- Cryotherapy for warts or precancerous lesions.
- Laser therapy for certain skin conditions.
Home Care Tips
Simple tips can aid in recovery.
- Keep the area clean and avoid touching it unnecessarily.
- Use over-the-counter pain relief if needed.
- Stay hydrated and maintain a healthy diet to support healing.
Patient Education & Prevention
Education is key to preventing skin issues.
- Regular skin checks for new or changing lesions.
- Use sunscreen to protect against UV damage.
- Avoid tanning beds and excessive sun exposure.
Billing and Coding Information
CPT Code: 11100
Category: Surgical Procedures
Common Modifiers:
- 25 - Significant, separately identifiable evaluation and management service by the same physician on the same day of the procedure.
- 59 - Distinct procedural service.
Average Cost and Insurance Coverage
Costs can vary based on location and insurance.
- Average cost ranges from $200 to $500.
- Most insurance plans cover medically necessary biopsies.
- Check with your insurance provider for specific coverage details.
Related CPT Codes
References and Sources