Heavy chain disease, in remission is a rare type of monoclonal gammopathy characterized by the production of abnormal heavy chain immunoglobulins. It is clinically significant as it can lead to various complications, including organ damage. The ICD-10 Code C88.21 facilitates accurate diagnosis, documentation, medical billing, and public health reporting, ensuring that healthcare providers can effectively manage and track this condition.
ICD-10 Code C88.21 represents Heavy chain disease, in remission, a condition where abnormal heavy chain immunoglobulins are produced, leading to potential complications. This code should be used in clinical documentation and billing when a patient is diagnosed with this condition and is currently in a state of remission, indicating a lack of active disease symptoms.
Heavy chain disease, in remission, is caused by the proliferation of B-lymphocytes that produce abnormal heavy chain immunoglobulins. The condition can progress to severe complications if not monitored and treated appropriately. Medical attention is crucial to manage symptoms and prevent potential organ damage.
ICD-10 Code C88.21 is utilized in SOAP notes to document the patient's symptoms, assessment findings, and treatment plans. It is relevant in both acute and chronic care settings, ensuring comprehensive documentation of the patient's condition and facilitating appropriate management strategies.
In SOAP notes, ICD-10 Code C88.21 connects subjective patient-reported symptoms and objective clinical findings to a formal diagnosis of Heavy chain disease, in remission. This code is essential for ensuring continuity of care, supporting accurate billing, and meeting EHR documentation standards.
Management of Heavy chain disease, in remission focuses on monitoring and supportive care, as the condition may lead to complications if not properly addressed.


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Learn moreICD-10 Code C88.21 is critical in medical billing, particularly in hospital, ER, or infectious disease care settings.
| CPT Code | Description |
|---|---|
| 85025 | Complete blood count (CBC) with automated differential. |
| 84155 | Immunoglobulin; heavy chains. |
| 36415 | Collection of venous blood by venipuncture. |
Common Questions About Using ICD-10 Code C88.21 for Heavy chain disease, in remission
What are the common symptoms of Heavy chain disease?
Common symptoms include fatigue, weight loss, and recurrent infections. Patients may also experience symptoms related to organ involvement, such as abdominal pain or swelling.
How is Heavy chain disease diagnosed?
Diagnosis typically involves serum protein electrophoresis to detect abnormal heavy chains, along with clinical evaluation and history taking.
What does remission mean in the context of Heavy chain disease?
Remission indicates that the patient is not currently experiencing active symptoms or complications related to Heavy chain disease, although monitoring is still necessary.
How often should patients with Heavy chain disease be monitored?
Patients should have regular follow-up appointments, typically every 3 to 6 months, to monitor serum protein levels and assess for any potential complications.
Clinical Notes
SOAP notes
DAP notes
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